Jianhong Dou

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An optimal electrode position and interventricular (VV) delay in cardiac resynchronization therapy (CRT) improves its success. However, the precise quantification of cardiac dyssynchrony and magnitude of resynchronization achieved by biventricular (BiV) pacing therapy with mechanical optimization strategies based on computational models remain scant. The(More)
Heart failure (HF) is associated with susceptibility to sudden cardiac death. However, the underlying mechanism of electrical instability and mechanical dysfunction associated with HF remains poorly understood. In this study, a new canine ventricular cell model based on the Hund-Rudy dynamic (HRd) model and recently published experimental data was developed(More)
The heart movement affects the body surface electrocardiogram (ECG) and magnetocardiography (MCG). However, in the previous MCG simulation studies, the heart was always assumed static and the heart movement was seldom taken into account. In this paper, we present a simulation study of MCG based on an electrodynamic heart model to investigate the effect of(More)
CVD (cardiovascular disease) is one of the biggest threats to human beings nowadays. An early and quantitative diagnosis of CVD is important in extending lifespan and improving people’s life quality. Coronary artery stenosis can prevent CVD. To diagnose the degree of stenosis, the inner diameter of coronary artery needs to be measured. To achieve such(More)
OBJECTIVE To validate the efficiency of an improved Demons deformable registration algorithm and evaluate its application in registration of the treatment image and the planning image in image-guided radiotherapy (IGRT). METHODS Based on Brox's gradient constancy assumption and Malis's efficient second-order minimization algorithm, a grey value gradient(More)
This paper presents a microcontroller system for target controlled infusion according to pharmacodynamic parameters of intravenous anesthetics. It can control the depth of anesthesia by adjusting the level of plasma concentrations. The system has the advantages of high precision, extending power and easy manipulation. It has been used in the clinical(More)
Tetralogy of Fallot (TOF) is the most common complex congenital heart disease (CHD) of the cyanotic type. Studies on ventricular functions have received an increasing amount of attention as the development of diagnosis and treatment technology for CHD continues to advance. Reasonable options for imaging examination and accurate assessment of preoperative(More)
Asynchronous electrical activation, induced by bundle branch block (BBB), can cause reduced ventricular function. However, the effects of BBB on the mechanical function of heart are difficult to assess experimentally. Many heart models have been developed to investigate cardiac properties during BBB but have mainly focused on the electrophysiological(More)
OBJECTIVE To develop a portable field anesthesia machine system suitable for the medical first-aid on the spot. METHODS The three-dimensional structure of PFAM was designed with modeling software of Pro/E and manufactured according to the GB9706.29 and other national standards. RESULT Due to its small footprint and very light weight, PFAM is completely(More)
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