Jianhe Yang

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The purpose of the study was to compare cytogenetic profiles and survivals between elderly and non-elderly Chinese patients with diffuse large B-cell lymphoma (DLBCL). We identified 50 patients with DLBCL and divided them by age into elderly (≥60 years) and non-elderly (< 60 years) groups. We detected deletion of P53 or translocations in Bcl-2, Bcl-6 or(More)
BACKGROUND Genetic background and environmental factors play an interactive role in the development of acute lymphocytic leukemia (ALL), and the human leukocyte antigen (HLA) system was noted as an important genetic factor in ALL. MATERIAL AND METHODS Due to the high diversity of HLA alleles, our present study assessed the possibility of an association of(More)
OBJECTIVE To explore the mechanism of NK cell dysfunction in patients with multiple myeloma (MM). METHODS The expression of inhibitory receptors (CD158a and CD158b) and activating receptors NKG2D and NCRs (NKp30, NKp44 and NKp46) on CD3-CD56+NK cell of 13 MM patients and 30 healthy controls were analyzed by flow cytometry. The concentration of soluble(More)
OBJECTIVE To investigate the prognostic significance of cytogenetic abnormalities, staging, patient factors, and the serum p53 protein concentration in Chinese non-Hodgkin lymphoma (NHL) patients. MATERIAL AND METHODS The study included 43 patients with NHL that were identified between August 2003 and December 2008. Patient clinical characteristics(More)
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