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Genuine, nondegraded PAMAM dendrimers self-assemble with siRNA into nanoscale particles that are efficient for siRNA delivery and induce potent endogenous gene silencing.
RNA interference (RNAi) was first literaturally reported in 1998 and has become rapidly a promising tool for therapeutic applications in gene therapy. In a typical RNAi process, small interfering… Expand
Multi-responsive hydrogels with high strength have great significance for potential applications in smart soft devices. However, it remains a challenge to incorporate multiple responsive moieties… Expand
Nanosized metal and polyaniline (PANi) composite spheres have been prepared via the polymerization of aniline using PdCl(2) or HAuCl(4) as the oxidant in a microemulsion system. The oxidization of… Expand
HIGHLIGHTSThe strength and deformation properties of cracked rock were studied.The acoustic emission and failure characteristics of cracked rock were investigated.The optimal selection of strength… Expand
HIGHLIGHTSAggregate gradation influences on dilatancy of cemented rockfill.Aggregate gradation effects on ultrasonic pulse velocity of cemented rockfill.The optimum gradation of aggregate particles… Expand
Low generational polyamidoamine (PAMAM) dendrimers with triethylene glycol (TEG) core and ester groups at the surface have been synthesized and investigated as templates for preparation of gold… Expand
It is of great significance for engineering safety, economic benefits, environmental protection, and sustainable development to investigate the strata stability in filling mining with cemented… Expand
In order to better understand groundwater influx and protection in coal mining extraction works, an in-house water flow apparatus coupled with an industrial rock testing system, known as MTS 815.02,… Expand
Abstract Investigating the dilatancy, acoustic emission and failure characteristics of fissured rock are significant to ensure their geotechnical stability. In this paper, the uniaxial and triaxial… Expand