Learn More
Biometrics is a rapidly developing technology that is to identify a person based on his or her physiological or behavioral characteristics. To ensure the correction of authentication, the biometric system must be able to detect and reject the use of a copy of a biometric instead of the live biometric. This function is usually termed " liveness detection ".(More)
We have shown before that constitutive DNA damage signaling represented by H2AX-Ser139 phosphorylation and ATM activation in untreated normal and tumor cells is a reporter of the persistent DNA replication stress induced by endogenous oxidants, the by-products of aerobic respiration. In the present study we observed that exposure of normal mitogenically(More)
Two different mechanisms are considered to be the primary cause of aging. Cumulative DNA damage caused by reactive oxygen species (ROS), the by-products of oxidative phosphorylation, is one of these mechanisms (ROS concept). Constitutive stimulation of mitogen- and nutrient-sensing mTOR/S6 signaling is the second mechanism (TOR concept). The flow- and laser(More)
In addition to its traditional role in the regulation of calcium homeostasis and bone metabolism, vitamin D also exhibits immunomodulatory, anti-proliferative and cancer preventive activities. Molecular mechanisms that confer the chemo-preventive properties to vitamin D are poorly understood. We previously reported that constitutive phosphorylation of(More)
Berberine (BRB), a natural alkaloid, has a long history of medicinal use in both Ayurvedic and old Chinese medicine. Recently, available as a dietary supplement, Berberine is reported to have application in treatment of variety diseases. Previously we observed that BRB inhibited mTOR/S6 signaling concurrently with reduction of the level of endogenous(More)
In this paper, an active shape model (ASM) based facial feature localization strategy is proposed, which employs a local binary pattern (LBP) probability model. Due to the computation simplicity and illumination insensitivity of LBP texture descriptor and the learning ability of the probability model, the algorithm is robust and fast. In addition,(More)
Face indexing and searching from videos can be widely used in multimedia applications, information mining and biometric recognition. This paper presents a novel method for effective indexing and searching in videos. Differing from traditional methods, we sequentially integrate visual appearance with temporal continuity and position continuity for face(More)
Treatment options for advanced metastatic thyroid cancer patients are limited. Vemurafenib, a BRAFV600E inhibitor, has shown promise in clinical trials although cellular resistance occurs. Combination therapy that includes BRAFV600E inhibition and avoids resistance is a clinical need. We used an in vitro model to examine combination treatment with(More)
State Machine Diagram (SMD) is one of the SysML behavior diagrams, but it is a kind of semi-formal model language. As a consequence, models can not be verified conveniently and efficiently, especially in real-time embedded system (RTES) field as there are no descriptions of time and probability in SMD. To address these problems, we extend SMD with time and(More)