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ARID2: A new tumor suppressor gene in hepatocellular carcinoma
The current knowledge about the relevance of ARID2 in HCC and the implication in future patient care is summarized.
A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway
The results indicate that Icaritin is able to inhibit malignant growth of HCICs and suggest that Icar itin may be developed into a novel therapeutic agent for effective treatment of HCC.
Recent advances in the ARID family: focusing on roles in human cancer
The molecular biology and clinical studies concerned with the role played by the ARID family in cancer are reviewed to contribute to the understanding of the initiation and progression of cancer from a novel point of view, as well as providing potential targets for cancer therapy.
Prognostic value of the albumin–bilirubin grade in patients with hepatocellular carcinoma: Validation in a Chinese cohort
The prognostic value of the newly raised objective liver function assessment tool, the albumin–bilirubin (ALBI) grade, in patients with hepatocellular carcinoma has not been fully validated. We aimed
RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis.
It is reported that RIPK1 is upregulated in human colorectal cancer and promotes cell proliferation when overexpressed in a colon cancer cell line and the RIPK 1-MCU pathway is identified as a promising target to treat coloreCTal cancer.
Prognostic relevance of number and ratio of metastatic lymph nodes in resected carcinoma of the ampulla of Vater.
LNR is a useful factor for predicting the prognosis of the radical treatment for CAV, whereas the number of metastatic lymph nodes is the most important factor.
Variants Identified by Hepatocellular Carcinoma and Chronic Hepatitis B Virus Infection Susceptibility GWAS Associated with Survival in HBV-Related Hepatocellular Carcinoma
The results suggest that HCC or CHB susceptibility loci might also affect the prognosis of patients with HBV-related HCC.
Clinicopathological features and surgical outcomes of four rare subtypes of primary liver carcinoma.
CCC is a low-degree malignancy and relatively favorably prognostic subtype of HCC, however, GCC, SC, and CHC are three rare high-degreemalignancy subtypes of H CC with poor prognosis.
Preoperative D-dimer and Gamma-Glutamyltranspeptidase Predict Major Complications and Survival in Colorectal Liver Metastases Patients After Resection1
The pre-operative D-dimer levels, GGT levels and CPDG score are reliable biomarkers to predict post-operative major complications or survival in CRLM patients after hepatic resection, which make it useful for C RLM patients in guiding surveillance approaches and prognosis assessments.
Preliminary results of sintilimab plus different dose of IBI305 (anti-VEGF monoclonal antibody) in patients with advanced hepatocellular carcinoma: A phase Ib study.
This study aimed to evaluate the safety and efficacy of sintilimab, a PD-1 blockade, plus IBI305, a biosimilar candidate of bevacizumab, in patients with advanced hepatocellula...