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The epithelial-mesenchymal transition (EMT) has been implicated in various pathophysiological processes, including cancer cell migration and distal metastasis. Reactive oxygen species (ROS) and insulin receptor substrate-1 (IRS-1) are important in cancer progression and regulation of EMT. To explore the biological significance and regulatory mechanism of(More)
Analysis of composite shapes recently receives increasing amount of research attention. Different from a silhouette, a composite shape rarely contains a complete envelope. In the paper, we propose a novel envelope extraction algorithm based on the Delaunay triangulation for composite shapes. By analyzing the spatial relationship among individual components(More)
The receiver function (RF) technique has been widely applied to investigate crustal and mantle layered structures using P-to-S converted (Ps) phases from velocity discontinuities. However, the presence of low-velocity (relative to that of the bedrock) sediments can give rise to strong reverberations in the resulting RFs, frequently masking the Ps phases(More)
Mitochondrial dysfunction and epithelial-to-mesenchymal transition (EMT) play important roles in cancer development and metastasis. However, very little is known about the connection between mitochondrial dysfunction and EMT. Tu translation elongation factor, mitochondrial (TUFM), a key factor in the translational expression of mitochondrial DNA, plays an(More)
YAP is a transcriptional co-regulator that plays important roles in various patho-physiological processes, including the survival and death of cells. However, the effect of YAP on apoptosis and EMT, simultaneously mediated by TGF-β1, is not known. In this study, we demonstrate that YAP can modulate cell fate of apoptosis versus EMT by acting as a surviving(More)
Nowadays, digital forensics has emerged as an important research field with applications of authenticity/integrality verification for digital data. In this paper, we focus on image forensic techniques and propose a blind scheme for image tampering identification which is capable to determine the tampering type. Since tampering operations bring in changes to(More)
Radon transform has widely used in various fields. It mainly uses different characteristics of seismic events in the transformation domain (τ-p domain) to separate different wave fields in seismic processing. Radon transform has a good effect in seismic event identification, wave filed separation, multiple suppression, velocity analysis et al. In(More)
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