Jiangjun Zhang

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Sirtuin 1 (Sirt1) is a deacetylase that regulates many cellular processes in the liver, and so far its role in endotoxemic liver injury is elusive. So we conditionally inactivate Sirt1 in murine hepatocytes to determine its role in d-galactosamine (GalN)/lipopolysaccharide (LPS)-induced liver damage, which is a well-established experimental model mimicking(More)
Many classification problems encountered in real-world applications exhibit a profile of imbalanced data. Current methods depend on data resampling. In fact, if the feature set provides a clear decision boundary, resampling may not be needed to solve the imbalanced classification problem. Therefore, this work proposes a feature learning method based on the(More)
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