Jianghua Lai

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The effects of long-term alcohol consumption on the mitogen-activated protein kinases (MAPKs) pathway and N-methyl-D-aspartate-type glutamate receptor 1 (GluN1) subunits in the mesocorticolimbic system remain unclear. In the present study, rats were allowed to consume 6% (v/v) alcohol solution for 28 consecutive days. Locomotor activity and behavioral signs(More)
Nearly one-quarter of all avian species is either threatened or nearly threatened. Of these, 73 species are currently being rescued from going extinct in wildlife sanctuaries. One of the previously most critically-endangered is the crested ibis, Nipponia nippon. Once widespread across North-East Asia, by 1981 only seven individuals from two breeding pairs(More)
Previous studies suggest that hippocampal CA1, CA3, and DG regions may have distinct roles in alcohol dependence. Extracellular signal-regulated kinases (ERKs) and Ca(2+)/calmodulin dependent protein kinase II (CaMKII) have been shown to contribute to the molecular mechanism underlying drug dependence and relapse, and there may be an interaction between the(More)
Histone acetylation/deacetylation is a crucial mechanism in memory formation and drug addiction. There is evidence suggesting that histone H3 acetylation may contribute to the long-term neural and behavioral responses to addictive drugs. In addition, the basolateral amygdala (BLA) is critically involved in the formation of cue-associated memories. However,(More)
Ezetimibe is a potent inhibitor of cholesterol absorption by enterocytes. Although ezetimibe minimally affects the absorption of triglyceride, it is unknown whether ezetimibe affects the secretion of the incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). It has been shown that ezetimibe-treated mice are(More)
OBJECTIVE To analyze the allele frequencies of 7 short tandem repeat (STR) loci (D12S1718, D12S1675, D12S358, D12S367, D12S1638, D12S1646 and D12S1682) on chromosome 12 among Kashing-Beck disease (KBD) patients and the control population living in the KBD areas and non-KBD area. METHODS EDTA-blood specimens were collected from 102 unrelated individuals of(More)
Magnesium alloys are potential biodegradable implants because of their outstanding biological performance and biodegradability in the bioenvironment. However, the rapid corrosion of magnesium and its alloys in human body fluids or blood plasma limits their clinical application. In the present work, we first fabricated porous micro-arc oxidation (MAO)(More)
More recently, forensic interest has focused on X-chromosomal markers and which are especially useful in paternity cases with daughters. Genetic polymorphism studies at 10 short tandem repeat (STR) loci on the X-chromosome (DXS6804, DXS6799, DXS8378, DXS7130, DXS7132, HPRTB, DXS7133, DXS7423, DXS101 and DXS6789) were carried out in Yunnan Nu population of(More)
Background Chronic abuse of heroin leads to long-lasting and complicated cognitive impairment. Dopamine receptors are critically involved in the impulsive drug-driven behavior and the altered attention, processing speed, and mental flexibility that are associated with higher relapse rates. However, the effects of the different dopamine receptors and their(More)