Jiangang Zhang

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A series of shikonin analogues with side chain variants have been synthesized and evaluated for antitumor activity. These novel analogues show a broad spectrum of in vitro cytotoxicity against various cancer cell lines. Additionally, some analogues were also found to have the ability to decrease the expression level of HIF-1alpha in breast cancer cells(More)
Five hundred and seventy nine Chinese patients with schizophrenia who met DSMIV criteria for the disorder were genotyped for alleles epsilon 2,3,4 of apolipoprotein E (APOE) gene. All were recruited from inpatients and outpatients attending a large mental health centre in Shanghai. Results were compared to APOE data on 1528 controls drawn from the same(More)
OBJECTIVE To assess the clinical outcomes of percutaneous coronary intervention (PCI) with single-stent versus double-stents implantation in distal unprotected left main coronary artery (ULMCA) bifurcation lesions and evaluate their merits and demerits in this clinical setting. METHODS 88 patients with distal ULMCA bifurcation lesions and treated with PCI(More)
Io this paper, a robust and efficient watermarking algorithm is proposed for copyright protection of digital images. The proposed algorithm can also be extended to video sequences. Based on Eo et al.'s image-in-image watermarking algorithm [I], the proposed algorithm uses an integer discrete cosine transform (IntDCT) [q. It is based on the IotDCT transform(More)
A simple and rapid method that uses synthesized magnetic graphene composites as both an adsorbent for enrichment and as a matrix in MALDI-TOF MS analysis was developed for the detection of nitropolycyclic hydrocarbons (nitro-PAHs) in PM2.5 samples. Three nitro-PAHs were detected down to sub pg μL(-1) levels based on calculations from an instrumental(More)
A novel rhodamine derivative 3-bromo-5-methylsalicylaldehyde rhodamine B hydrazone (BMSRH) has been synthesized by reacting rhodamine B hydrazide with 3-bromo-5-methylsalicylaldehyde and developed as a new colorimetric probe for the selective and sensitive detection of Cu2+. Addition of Cu2+ to the solution of BMSRH results in a rapid color change from(More)
The analysis of the vast storehouse of email content accumulated or produced by individual users has received relatively little attention other than for specific tasks such as relationship. Current email analysis in standard client applications consists of keyword based matching techniques for relationship of email files. We have implemented a tool, called(More)