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Multiplexed, High Density Electrophysiology with Nanofabricated Neural Probes
Extracellular electrode arrays can reveal the neuronal network correlates of behavior with single-cell, single-spike, and sub-millisecond resolution. However, implantable electrodes are inherentlyExpand
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High-resolution three-dimensional extracellular recording of neuronal activity with microfabricated electrode arrays.
Microelectrode array recordings of neuronal activity present significant opportunities for studying the brain with single-cell and spike-time precision. However, challenges in device manufacturingExpand
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Variability of acute extracellular action potential measurements with multisite silicon probes
Device miniaturization technologies have led to significant advances in sensors for extracellular measurements of electrical activity in the brain. Multisite, silicon-based probes containingExpand
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Wiring nanoscale biosensors with piezoelectric nanomechanical resonators.
Nanoscale integrated circuits and sensors will require methods for unobtrusive interconnection with the macroscopic world to fully realize their potential. We report on a nanoelectromechanical systemExpand
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  • Open Access
Abstract 4877: Discovery of novel and potent inhibitors of indoleamine-2,3-dioxygenase (IDO1) for cancer immunotherapy
Indoleamine-2,3-dioxygenase (IDO1) is an immune regulatory enzyme that oxidizes tryptophan to kynurenine. IDO1 is overexpressed in numerous tumor cells that block T-cell activation, induce T-cellExpand