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BACKGROUND Pancreas transplantation is a valid therapy for patients with type 1 diabetes mellitus (IDDM). This study was undertaken to establish a stable pig model of whole pancreatoduodenal allotransplantation of physiologically coincidence for pancreas transplantation. METHODS The IDDM pig model was made by resection of the pancreas from the recipient.… (More)
OBJECTIVE To improve the procedures of pancreas-duodenal transplantation in swines in order to establish a technically stable model that accords with the physiological situation. METHODS The whole pancreatoduodenal graft was harvested with in situ flush using 4 degrees C preservation solution. Type 1 diabetes was induced surgically by total… (More)
In the title compound, C(15)H(18)ClNO(2), the amide group is coplanar with the chloro-phenyl group, making a dihedral angle of 1.71 (12)°. The cyclo-penta-none ring adopts a twist conformation. A weak intra-molecular C-H⋯O hydrogen bond is observed. Mol-ecules are linked into cyclic centrosymmetric dimers by paired N-H⋯O hydrogen bonds.