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In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine
- Jiang Luo, S. Vashishtha, E. Hawes, G. Mckay, K. Midha, J. Fang
- Chemistry, Medicine
- Biopharmaceutics & drug disposition
- 1 October 2011
In vitro studies were conducted to identify the hepatic cytochrome P450 (CYP) enzymes responsible for the oxidative metabolism of loxapine to 8‐hydroxyloxapine, 7‐hydroxyloxapine, N‐desmethylloxapine… Expand
One-Pot Synthesis of Cu-Nanocluster-Decorated Brookite TiO2 Quasi-Nanocubes for Enhanced Activity and Selectivity of CO2 Photoreduction to CH4.
- J. Jin, Jiang Luo, L. Zan, T. Peng
- Materials Science, Medicine
- Chemphyschem : a European journal of chemical…
- 17 November 2017
A new kind of metallic Cu-loaded brookite TiO2 composite, in which Cu nanoclusters with a small size of 1-3 nm are decorated on brookite TiO2 quasi nanocube (BTN) surfaces (hereafter referred to as… Expand
Quantitative assessment of bladder neck compliance by using transvaginal real-time elastography of women.
To assess the feasibility of using ultrasound real-time elastography (RTE) to measure bladder neck compliance, we performed real-time elastography measurements by manually applying repetitive… Expand
Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors
- Guoyi Yan, Manzhou Hou, +4 authors Rui Li
- Biology, Medicine
- Chemical biology & drug design
- 1 February 2018
Bromodomain is a recognition module in the signal transduction of acetylated histone. BRD4, one of the bromodomain members, is emerging as an attractive therapeutic target for several types of… Expand