• Publications
  • Influence
Non-tuberculous mycobacteria in China
Infection with non-tuberculous mycobacteria (NTM) is relatively rare in areas that are high-endemic for tuberculosis. We identified 126 strains of NTM in respiratory specimens collected by theExpand
  • 7
  • 3
Evaluation of quality control system for direct smear microscopy in National Tuberculosis Program in China
Quality Control(QC)of direct smear microscopy for acid-fast bacilli plays a great role in National Tuberculosis Program.Since 1994,the quality control system was established by National TB ControlExpand
  • 1
Clinical application on rapid detection of mycobacterium tuberculosis using Hyperbranched Rolling circle amplification
Objective A highly sensitive,specific method,Hyperbranched Rolling circle amplification(HRCA),was optimized and used to detect M.tuberculosis.Methods The sequences of the 5' terminal and 3' terminalExpand
Genotyping and drug resistance analysis of Mycobacterium tuberculosis from China
Objective To study the genotypes of representative Mycobacterium tuberculosis (M.tuberculosis) strains from China with spacer oligonucleotide typing (spoligotyping),and to investigate the prevalenceExpand
Treatment outcomes of linezolid for multidrug-resistant tuberculosis: a systematic review and meta-analysis
目的 初步评价利奈唑胺治疗耐多药结核(MDR-TB)的有效性与安全性.方法 检索Cochrane图书馆临床对照试验库、Pubmed,Embase,CBM、CNKI、Wanfang Date等电子数据库.对符合纳入标准的临床研究进行统计分析.结果Expand
Detection of Mycobacterium tuberculosis by loop-mediated isothermal amplification assay targeting different genes
目的 探讨针对hspX、gyrB、IS6110靶基因设计引物,采用环介导等温扩增技术(LAMP)检测对结核病的诊断价值.方法Expand
Analysis of human resource situation of laboratories of tuberculosis control program
目的 了解全国疾病预防控制体系结核病实验室人力资源现状,为提高结核病实验室工作质量、加强结核病实验室服务提供参考.方法 通过2009年实验室调查表获得全国疾病预防控制体系结核病实验室人员资料,对人员学历、职称、年龄、专业及专兼职情况等人员基本构成情况进行分析.结果Expand
Co-expression of protein of M.tuberculosis with molecular chaperone
目的 研究共同表达分子伴侣能否提高结核分枝杆菌编码基因的表达效率及被表达蛋白的生物活性.方法 将携带有结核分枝杆菌编码基因的表达质粒Rv3790::pET16b、Rv3791::pET16b与能够同时表达3个分子伴侣DnaK、DnaJ和GrpE的质粒pkJE7共同在大肠埃希菌BL21(DE3)表达,之后对所获得的蛋白通过聚丙烯酰胺凝胶电泳和免疫印记分析(WesternExpand
Identification of strains isolated from tuberculosis outbreak in a high school
目的鉴定从某中学结核病爆发分离菌株的种属。方法2006年5—8月辽宁省某高级中学部分学生出现活动性结核病的临床表现,从10例涂片阳性患者的痰标本中分离得到3份菌株经表型鉴定方法,传统生化方法,扩增hupB基因、dnaA-dnaN和NTF-1区;Spoligotyping以及MIRU基因分型;16S rRNA基因、16S-23SExpand