Jianfeng Chen

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A fair and efficient service flow management architecture for IEEE802.16 Broadband Wireless Access (BWA) systems is proposed for TDD mode. Comparing with the traditional fixed bandwidth allocation, the proposed architecture adjusts uplink and downlink bandwidth dynamically to achieve higher throughput for unbalanced traffic. A deficit fair priority queue(More)
An object on the Semantic Web is likely to be denoted with multiple URIs by different parties. Object coreference resolution is to identify "equivalent" URIs that denote the same object. Driven by the Linking Open Data (LOD) initiative, millions of URIs have been explicitly linked with owl:sameAs statements, but potentially coreferent ones are still(More)
This paper proposes a new integrated QoS architecture for IEEE 802.16 Broadband Wireless MAN in TDD mode. After analyzing the current strategies to provide IntServ for the Internet connection via IEEE802.16-2004 WirelessMAN, a mapping rule and a fast signaling mechanism for providing both InterServ and DiffServ are given under Point to Multi-Point (PMP) and(More)
In this paper an automated bathroom activity monitoring system based on acoustics is described. The system is designed to recognize and classify major activities occurring within a bathroom based on sound. Carefully designed HMM parameters using MFCC features are used for accurate and robust bathroom sound event classification. Experiments to validate the(More)
Integrin alpha(4)beta(7) mediates rolling adhesion in Ca(2+) and Ca(2+) + Mg(2+), and firm adhesion in Mg(2+) and Mn(2+), mimicking the two key steps in leukocyte accumulation in inflamed vasculature. We mutated an interlinked linear array of three divalent cation-binding sites present in integrin beta-subunit I-like domains. The middle, metal ion-dependent(More)
RATIONALE Vascular calcification is a hallmark of atherosclerosis, a major cause of morbidity and mortality in the United States. We have previously reported that the osteogenic transcription factor Runx2 is an essential and sufficient regulator of calcification of vascular smooth muscle cells (VSMC) in vitro. OBJECTIVE To determine the contribution of(More)
Antibody blockade of the inhibitory CTLA-4 pathway has led to clinical benefit in a subset of patients with metastatic melanoma. Anti-CTLA-4 enhances T cell responses, including production of IFN-γ, which is a critical cytokine for host immune responses. However, the role of IFN-γ signaling in tumor cells in the setting of anti-CTLA-4 therapy remains(More)
The lymphocyte homing receptor integrin α(4)β(7) is unusual for its ability to mediate both rolling and firm adhesion. α(4)β(1) and α(4)β(7) are targeted by therapeutics approved for multiple sclerosis and Crohn's disease. Here, we show by electron microscopy and crystallography how two therapeutic Fabs, a small molecule (RO0505376), and mucosal adhesion(More)