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Relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), and blood flow speed are key parameters that characterize cerebral hemodynamics. We used contrast-enhanced functional micro-ultrasound (fMUS) imaging employing a disruption-replenishment imaging sequence to quantify these hemodynamic parameters in the anesthetized rat brain. The(More)
Healthy cerebral microcirculation is crucial to neuronal functioning. We present a new method to investigate microvascular hemodynamics in living rodent brain through a focal cranial window based on high-frequency ultrasound imaging. The method has a temporal resolution of 40ms, and a 100μm in-plane and 600μm through-plane spatial resolution. We use a(More)
Finite element method (FEM)-based scientific numerical simulations are often computing-extensive and grid platform can speed up the simulation progress significantly. However, the coupling of FEM-based simulation tasks with grid platform isn't so straightforward. Adopting the service-oriented architecture (SOA), we develop a general service-oriented grid(More)
BACKGROUND To date, the relationships between childhood neglect, hypothalamic-pituitary-adrenal (HPA) axis functioning and dysfunctional attitude in depressed patients are still obscure. METHODS The Childhood Trauma Questionnaire (CTQ) was used to assess childhood emotional neglect and physical neglect. Twenty-eight depressed patients with childhood(More)
Recent development of ICN technologies mostly focused on data caching, and data publication and subscription to improve the efficiency of data transmission. The issues of monopoly of users' data and social relations by ASPs (Application Service Provider) have been ignored. This monopoly causes some problems such as the hijack of users by a handful of giant(More)
In the current Internet architecture, application service providers (ASPs) own users' data and social groups information, which made a handful of ASP companies growing bigger and bigger and denied small and medium companies from entering this business. We propose a new architecture, called Application Independent Information Infrastructure (AI3). The design(More)
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