Jianfang Hu

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T cell development is critically dependent on both the environment and signals delivered by the T cell Receptor (TCR). The Tec family kinase Itk has been suggested to be an amplifier of signals emanating from the TCR and the loss of Itk partially affects most stages of thymopoiesis. Loss of Itk also differentially affects the development of conventional vs.(More)
  • Guo Fu, Sébastien Vallée, Vasily Rybakin, Marielena V. McGuire, Jeanette Ampudia, Claudia Brockmeyer +10 others
  • 2009
Themis (Thymocyte expressed molecule involved in selection), a member of a family of proteins with unknown functions, is highly conserved among vertebrates. Here we found that Themis is expressed in high amounts in thymocytes between the pre-T cell receptor (TCR) and positive selection checkpoints, and in low amounts in mature T cells. Themis-deficient(More)
S a mp l e s S a mp l e s HOG HOG S a mp l e s HOG S a mp l e s HOG Figure 1: Visualization of HOG features from two activity snapshots in RGB (gray) and depth channel respectively. As shown, the HOG features from both channels of the same activity unveils similar " gist " structure of that activity. The emergence of low-cost depth sensors (e.g., the(More)
Human action can be recognised from a single still image by modelling Human-object interaction (HOI), which infers the mutual spatial structure information between human and object as well as their appearance. Existing approaches rely heavily on accurate detection of human and object, and estimation of human pose. They are thus sensitive to large variations(More)
BACKGROUND Exposure to Staphylococcal Enterotoxin B (SEB), a bacterial superantigen secreted by the Gram-positive bacteria Staphyloccocus aureus, results in the expansion and eventual clonal deletion and anergy of Vbeta8+ T cells, as well as massive cytokine release, including Interleukin-2 (IL-2). This IL-2 is rapidly secreted following exposure to SEB and(More)
Gibberellins (GAs) have been widely used for many years to induce seedless grapevine and increase fruit set in production. However, the role of GAs and how they crosstalk with auxin and cytokinin during fruit set in grapevine remains unclarified. To investigate their role, GA3, 4-chlorophenoxyacetic acid (4-CPA), 6-benzylaminopurine (6-BA), and different(More)
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