Jiande D. Z. Chen

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The time delay estimation (TDE) is an important issue in modern signal processing and it has found extensive applications in the spatial propagation feature extraction of biomedical signals as well. Due to the extreme complexity and variability of the underlying systems, biomedical signals are usually nonstationary, unstable and even chaotic. Furthermore,(More)
The frequency content of many biomedical signals can change rapidly with time. Conventional Fourier spectral analysis techniques are insufficient for analyzing the time-varying spectral content of these signals. By mapping a one-dimensional function of time (or frequency), the time-frequency representation can localize the signal energy in both the time and(More)
Intestinal electric stimulation (IES) has been shown to produce an inhibitory effect on gastric motility and secretion. The possible central mechanism of this entero-gastric inhibitory effect induced by IES is unknown. The objective of this study was to evaluate the effects of various IES on the activity of neurons in nucleus tractus solitarii (NTS). We(More)
During the last decades, numerous studies have been performed to investigate the effects and mechanisms of acupuncture or electroacupuncture (EA) on gastrointestinal motility and patients with functional gastrointestinal diseases. A PubMed search was performed on this topic and all available studies published in English have been reviewed and evaluated.(More)
This study was done to introduce new parameters derived by time frequency analysis of heart rate variability data. Four simulation experiments were carried out to compare the short-time Fourier transform (STFT) analysis method to the traditional overall spectral analysis method. Sinusoidal signals were generated with identical total power in the(More)
Myoelectrical recordings of the gut contains slow waves (slow rhythmicity) and spikes (fast rhythmicity). While the slow wave determines the frequency and propagation of gastrointestinal contractions, spike activities are directly associated with the contractions. Traditionally, spikes are extracted from the myoelectrical recording using high-pass/bandpass(More)
Electrogastrography (EGG) is a non-invasive method for the measurement of gastric myoelectrical activity. It was first discovered in 1921 and popularized in 1990s. EGG is attractive because it is non-invasive. However, due to its non-invasive nature, there have also been controversies regarding validity and applications of EGG. The aim of this review is to(More)
BACKGROUND Gastric electrical stimulation (GES) has been shown to be effective in inducing satiety in patients with obesity, as well as in treating nausea and vomiting in patients with gastroparesis. It is conceivable that these effects are mediated via the central nervous system, although there is a lack of studies or evidences. The aims of this study were(More)
BACKGROUND Our primary goals were to investigate the effects of two-channel gastric pacing on gastric myoelectrical activity, and energy consumption with the secondary intent to monitor gastric emptying and symptoms in patients with severe diabetic gastroparesis. METHODS Four pairs of temporary pacing wires were inserted on the serosa of the stomach at(More)
Gastric pacing has been investigated as a potential treatment for gastroparesis. New pacing protocols are required to improve symptom and motility outcomes; however, research progress has been constrained by a limited understanding of the effects of electrical stimulation on slow-wave activity. This study introduces high-resolution (HR) "entrainment(More)