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BACKGROUND Mitochondrial DNA (mtDNA) haplogroups and single nucleotide polymorphisms (mtSNP) have been shown to play a role in various human conditions including aging and some neurodegenerative diseases, metabolic diseases and cancer. METHODS To investigate whether mtDNA haplogroups contribute to the occurrence of cancer in a specific Chinese population,(More)
PURPOSE To evaluate the role of mtDNA in breast cancer. METHODS We carried out an investigation into the mtDNA major control region or D-loop region and an essential and the largest mtDNA protein-coding gene, NADH dehydrogenase subunit 5 (ND5), together with a mitochondrial haplogroup analysis in 64 patients with breast cancer (BC) and 54 patients with(More)
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