Jianchao Zhang

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Epithelial-mesenchymal transition is a change of cellular plasticity critical for embryonic development and tumor metastasis. CDK5 is a proline-directed serine/threonine kinase playing important roles in cancer progression. Here we show that CDK5 is commonly overexpressed and significantly correlated with several poor prognostic parameters of breast cancer.(More)
Building information modelling (BIM) provides architectural 3D visualization and a standardized way to share and exchange building information. Recently, there has been an increasing interest in using BIM, not only for design and construction, but also the post-construction management of the built facility. With the emergence of smart built environment(More)
Epithelial-mesenchymal transition is a change of cellular plasticity critical for embryonic development and tumor metastasis. CDK5 is a proline-directed serine/threonine kinase playing important roles in cancer progression. Here we show that CDK5 is commonly overexpressed and significantly correlated with several poor prognostic parameters of breast cancer.(More)
With the rapid development of computer and information automatics, advanced manufacturing technologies (such as numerical control technology and computer-aided manufacturing) have been invented and matured. In the face of fierce competition in the international market of 21st century, high-tech application becomes one of the main battle fields. In recent(More)
Numb is an endocytic protein that plays crucial roles in diverse cellular processes such as asymmetric cell division, cell migration and differentiation. However, the molecular mechanism by which Numb regulates endocytic trafficking is poorly understood. Here, we demonstrate that Numb is a docking regulator for homotypic fusion of early endosomes (EEs).(More)
Transferrin receptor (TFR) is an important iron transporter regulating iron homeostasis and has long been used as a marker for clathrin mediated endocytosis. However, little is known about its additional function other than iron transport in the development of central nervous system (CNS). Here we demonstrate that TFR functions as a regulator to control(More)
Syntrophic methanogenesis is an essential link in the global carbon cycle and a key bioprocess for the disposal of organic waste and production of biogas. Recent studies suggest direct interspecies electron transfer (DIET) is involved in electron exchange in methanogenesis occurring in paddy soils, anaerobic digesters, and specific co-cultures with(More)
The details for affiliations 1–3 were incorrect in the original HTML version of this Article. The affiliations were incorrectly listed as including ''Auckland, New Zealand''. These affiliations should include ''Changchun, China''. The correct affiliations are listed above. This has now been corrected in the HTML and PDF version of the Article.