Jianbo Zhao

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It is very common chromatographic practice to optimize resolution by making changes in selectivity by systematically varying key retention controlling factors. In many instances, a change in conditions merely results in monotonic, systematic variation in the relative retention of all pairs of peaks. Useful or "effective" changes in selectivity generally(More)
We have solved at 1. 07: Å resolution the X-ray crystal structure of a polyriboadenylic acid (poly(rA)) parallel and continuous double helix. Fifty-nine years ago, double helices of poly(rA) were first proposed to form at acidic pH. Here, we show that 7-mer oligo(rA), i.e. rA7, hybridizes and overlaps in all registers at pH 3.5 to form stacked double(More)
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