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Review for carrageenan-based pharmaceutical biomaterials: favourable physical features versus adverse biological effects.
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Inhibiting Delta-6 Desaturase Activity Suppresses Tumor Growth in Mice
TLDR
It is shown that D 6D activity is upregulated during melanoma and lung tumor growth and that suppressing D6D activity, either by RNAi knockdown or a specific D6d inhibitor, dramatically reduces tumor growth.
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Effects of Coptis extract combined with chemotherapeutic agents on ROS production, multidrug resistance, and cell growth in A549 human lung cancer cells
TLDR
As potential adjuvants to chemotherapy for non–small cell lung cancer, COP and BER increase ROS production, reduce MDR, and enhance the inhibitory effects of chemotherapeutic agents on A549 cell growth.
View on Springer
Ultrasound-Assisted Extraction, Antioxidant and Anticancer Activities of the Polysaccharides from Rhynchosia minima Root
TLDR
Box-Behnken design was used to optimize the experimental conditions for ultrasound-assisted extraction of polysaccharides from Rhynchosia minima root and showed that poly Saccharide fractions from PRM have the potential to be developed as natural antioxidants and anticancer ingredients for the food and pharmaceutical industries.
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Protective Effects of Otophylloside N on Pentylenetetrazol-Induced Neuronal Injury In vitro and In vivo
TLDR
The results revealed that OtoN treatment may attenuate PTZ-induced morphology changes, cell death, LDH efflux in embryonic neuronal cells of C57BL/6J mice, and convulsive behavior in zebrafish, and the first investigation of the neuroprotective effects of Oto N, which might be developed as a novel antiepileptic drug.
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A review on phytochemical and pharmacological properties of Litsea coreana
TLDR
A systematic review of the ethnopharmacological applications, phytochemistry, and pharmacological activities and molecular mechanisms of L. coreana should be useful for further study and application of this medicinal herb.
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Transgenic n-3 PUFAs enrichment leads to weight loss via modulating neuropeptides in hypothalamus
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Cyanidin-3-o-β-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-κB Signalling.
TLDR
The data indicate that Cy-3-g induces megakaryocyte apoptosis via the inhibition of NF-ÎşB signalling, which may play important roles in regulating thrombopoiesis.
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Cyanidin-3-O-β-glucoside, a Natural Polyphenol, Exerts Proapoptotic Effects on Activated Platelets and Enhances Megakaryocytic Proplatelet Formation.
TLDR
It is found that Cy-3-g promotes activated platelet apoptosis and enhances megakaryocyte proliferation, differentiation, and proplatelet formation in vitro and significantly increased phosphatidylserine exposure compared with control.
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Simultaneous determination of seven phenolic acids in three Salvia species by capillary zone electrophoresis with β-cyclodextrin as modifier.
TLDR
Under the optimum conditions, samples of Danshen and related medicinal plants were analyzed using the developed method with high separation efficiency, indicating the good repeatability of the proposed method.
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