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BACKGROUND The objective of this study was to prepare, characterize, and evaluate a folate-modified self-microemulsifying drug delivery system (FSMEDDS) with the aim to improve the solubility of curcumin and its delivery to the colon, facilitating endocytosis of FSMEDDS mediated by folate receptors on colon cancer cells. METHODS Ternary phase diagrams(More)
Currently, targeted nanoparticles (NPs) are rapidly being developed to overcome various bottlenecks of antitumor agents, such as poor solubility in aqueous solution, poor pharmacokinetics, a lack of selectivity and undesirable side effects in healthy tissues. In recent years, chitosan, a cationic polysaccharide, has been widely explored for the targeted(More)
In this study, the authors consider the asymptotic capacity of wireless multicast and unicast transmission schemes in a spectrum-sharing system. In these schemes, a secondary access point (SAP) utilises the licensed spectrum of an active primary user (PU) to send a common information to multiple secondary users simultaneously, as long as the interference(More)
Lung-targeting cisplatin-loaded poly(lactic-co-glycolic) acid microspheres (CDDP-PLGA-MS) were prepared by a solvent evaporation method. The uniform design was used to optimize the technology of preparation, the appearance and size distribution were examined by scanning electron microscope, and the aspects such as in vitro release characteristics,(More)
In this letter, a novel linear transmission strategy to design the linear precoding matrix (PM) at base station (BS) and the beamforming matrix (BM) at relay station (RS) for multipleinput multiple-output (MIMO) relaying broadcast channels with direct channel (DC) is proposed, in which a linear PM is designed at BS based on DC, and the RS utilizes the PM,(More)
In this paper, we consider the capacity of a multicast network, where a single-antenna secondary base station (SBS) utilizes the spectrum licensed to primary users (PUs) to broadcast the same information to multiple secondary users (SUs) with a single-antenna simultaneously, when the interference received by PUs is less than a predefined threshold. Based on(More)
ETHNOPHARMACOLOGICAL RELEVANCE Salvia miltiorrhiza var. alba roots are used as the Chinese traditional medicine Danshen for the treatment of cardiovascular diseases in local clinical practice. Tanshinones are the major effective constituents of S. miltiorrhiza var. alba roots, but only tanshinone IIA, tanshinone I, cryptotanshinone, and(More)
Network coding is considered as a promising technique to improve diversity gain and network throughput in multi-source relay systems. This paper presents an opportunistic network coded cooperation scheme in wireless multi-unicast system with non-ideal source-relay channels. In the conventional network-coding-based cooperation schemes, the relay merges the(More)
In this paper, we consider a scenario where a secondary base station (SBS) with K antennas utilizes the licensed spectrum of a single primary user (PU) to send the same information to N secondary users (SUs). The SBS selects only one antenna out of the K antennas by using maximum signal power to leak interference power ratio strategy (SLIR). Using(More)
This paper addresses bounds on the transmission capacities of two coexisting wireless networks (a primary and a secondary network), where each with multiple antennas shares the same spectrum and operates in the same geographic region. In the two coexisting network, the secondary (SR) network limits its interference to the primary (PR) network by carefully(More)