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It has been well recognized that a deficit of numbers and function of CD4+CD25+Foxp3+ cells (Treg) is attributed to the development of some autoimmune diseases; however, there are controversial data regarding the suppressive effect of Treg cells on the T cell response in systemic lupus erythematosus (SLE). Additionally, IL-17-producing cells (Th17) have(More)
BACKGROUND This study was conducted to clarify the effect of the inhibiting action of inhibin on porcine granulosa cell proliferation and function, and to investigate the underlying intracellular regulatory molecular mechanisms. METHODS Porcine granulosa cells were cultured in vitro, and were treated with an anti-inhibin alpha subunit antibody, with or(More)
It has been well recognized that TGF-β is able to induce CD4(+)CD25(+)Foxp3(+) suppressor/regulatory T (iTreg) cells and IL-2 facilitates iTreg induction and expansion, however, only half of TGF-β-induced CD4(+)CD25(+) cells express Foxp3 and remaining CD4(+)CD25(+)Foxp3- cells may represent effector cells. Whether other factor(s) can increase Foxp3(More)
Epigenetic modifications, including DNA methylation, histone modifications, RNA epigenetics and nucleosome remodeling, are important for gene transcription, but such modifications do not change the coding sequence of the gene. Although these events are heritable, they are potentially reversible, thus opening up opportunities for the therapy of cancer. So(More)
Triggering receptor expressed on myeloid cells (TREM) is a cell-surface receptor primarily expressed on macrophages. Here, two novel TREM genes, AcTREM1 and AcTREM2, were identified from Anas cygnoides. AcTREM1 cDNA contained a putative signal peptide, two IG domains, and a transmembrane domain. The deduced AcTREM2 sequence also contained a signal peptide,(More)
The Yangzhou goose is a long-day breeding bird that has been increasingly produced in China. Artificial lighting programs are used for controlling its reproductive activities. This study investigated the regulations of photostimulation and photorefractoriness that govern the onset and cessation of the breeding period. Increasing the daily photoperiod from 8(More)
The quadratic shortest path (QSP) problem is to find a path from a node to another node in a given network such that the total cost includes two kinds of costs, say direct cost and interactive cost, is minimum. The direct cost is the cost associated with each arc and the interactive cost occurs when two arcs appear simultaneously in the shortest path. In(More)
Based on the data of the first wave of the Chinese Family Panel Study in 2010, this paper studies the relationship of divorce risk and four variables related to children in China: premarital births and number, age, and gender of children. We find that all four variables have significant effects on divorce risk. Specifically, (1) couples who have premarital(More)
This study was carried out to induce out-of-season breeding, in the summer, and to achieve high reproductive performance using artificial photoperiod manipulation in the long-day breeding Yangzhou goose. Young geese were subject to a two-phase short-to-long (group A) or a three-phase (long-short-long; group B) photoperiod program February through October.(More)