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Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study

A novel bat-borne CoV was identified that is associated with severe and fatal respiratory disease in humans and the amino acid sequence of the tentative receptor-binding domain resembles that of SARS-CoV, indicating that these viruses might use the same receptor.
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O-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesis

It is reported that O-linked GlcNAcylation (O-GlcNAc) and O-GlCNAc transferase (OGT) were markedly increased in HPV-caused cervical neoplasms relative to normal cervix, whereas O-glcNAcase (OGA) levels were not altered.
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Diet folate, DNA methylation and polymorphisms in methylenetetrahydrofolate reductase in association with the susceptibility to gastric cancer.

The effect of MTHFR C677T polymorphisms on the risk of gastric cancer was modified by folate intake and methylation status of MGMT (P for interaction <0.05), and individuals who had an intake of folate above 310 μg/day showed protective effects against Gastric cancer risk.
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Exosomal miR-1228 From Cancer-Associated Fibroblasts Promotes Cell Migration and Invasion of Osteosarcoma by Directly Targeting SCAI

Evidence is provided that CAF exosomal miR-1228 is able to promote osteosarcoma invasion and migration by targeting SCAI, which may represent a critical therapeutic target for osteosARcoma treatment.
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LKB1 Inhibits HPV-Associated Cancer Progression by Targeting Cellular Metabolism

It is proposed that LKB1 acts as a safeguard against HPV-stimulated aerobic glycolysis and tumor progression and may eventually aid in the development of therapeutic strategy for HPV-associated malignancies by targeting cell metabolism.
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LKB1 reduces ROS-mediated cell damage via activation of p38

It is demonstrated that L KB1 controls the levels of intracellular reactive oxygen species (ROS) and protects the genome from oxidative damage and the importance of targeting ROS signaling as a potential therapeutic strategy for cancer cells lacking LKB1 is highlighted.
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SIRT6/NF-κB signaling axis in ginsenoside Rg1-delayed hematopoietic stem/progenitor cell senescence.

Rg1 may fight against Sca-1+HSC/HPC senescence induced by t-BHP through regulating SIRT6-NF-κB signaling pathway.
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[Investigation on the epidemiology of Far-East tick-borne spotted fever in the Northeastern area of China].

Nine cities from the east part of the Northeastern areas of China were confirmed of having R. heilongjiangensis infection and it was demonstrated that in those above-mentioned areas, there had been an existing natural foci of Far East tick-borne spotted fever.
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Ginsenoside Rg1 enhances the resistance of hematopoietic stem/progenitor cells to radiation-induced aging in mice

Administration of ginsenoside Rg1 enhances the resistance of HSC/HPCs to ionizing radiation-induced senescence in mice by inhibiting the oxidative stress reaction, reducing DNA damage, and regulating the cell cycle.
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MiR-139-5p/SLC7A11 inhibits the proliferation, invasion and metastasis of pancreatic carcinoma via PI3K/Akt signaling pathway.

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