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Development of the Chinese Personality Assessment Inventory
A combined "emic-etic" approach was adopted to develop an indigenous omnibus personality inventory for the Chinese people. The Chinese Personality Assessment Inventory (CPAI) consists of constructsExpand
Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis.
TLDR
In conclusion, antipsychotic-related weight gain is polygenic and associated with specific genetic variants, especially in genes coding for antipsychotics pharmacodynamic targets. Expand
White matter development in adolescence: diffusion tensor imaging and meta-analytic results.
TLDR
The data suggest that abnormal maturation of the SLF during adolescence may be a key target in the neurodevelopment of schizophrenia. Expand
Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction
TLDR
This article reviews the pharmacogenetic literature from early 1990s to 2010, focusing on two aspects of drug action: pharmacokinetics and pharmacodynamics. Expand
Efficacy and safety of individual second-generation vs. first-generation antipsychotics in first-episode psychosis: a systematic review and meta-analysis.
TLDR
In FES, olanzapine, amisulpride and, less so, risperidone and quetiapine showed superior efficacy, greater treatment persistence and less EPS than FGAs. Expand
D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis.
TLDR
The authors conducted the first meta-analysis to examine the relationship between DRD2 polymorphisms and antipsychotic drug response in schizophrenia patients, finding that variation in the DRD(2) gene is associated with clinical response to antipsychotics. Expand
A Randomized Comparison of Aripiprazole and Risperidone for the Acute Treatment of First-Episode Schizophrenia and Related Disorders: 3-Month Outcomes.
TLDR
Overall, if the potential for akathisia is a concern, low-dose risperidone as used in this trial maybe a preferred choice over aripiprazole, but aripIPrazole would be the preferred choice in most situations based upon metabolic outcome advantages and some symptom advantages within the context of similar positive symptom response between medications. Expand
Neuropsychological Test Performance to Enhance Identification of Subjects at Clinical High Risk for Psychosis and to Be Most Promising for Predictive Algorithms for Conversion to Psychosis: A
TLDR
CHR has mild to moderate globally distributed neuropsychological performance deficits that lie between FEP and HCs, but they overlap, reducing their current utility for risk stratification. Expand
Pharmacogenetics of antipsychotics: recent progress and methodological issues
TLDR
Recent advances as reviewed in this article push the field closer to routine clinical utilization of pharmacogenetic testing, and larger sample sizes, better phenotype characterization, and careful consideration of study design issues will help to elevate antipsychotic pharmacogenetics to its next level. Expand
Genetic variation in BDNF is associated with antipsychotic treatment resistance in patients with schizophrenia
TLDR
BDNF appears to have a strong association with antipsychotic treatment resistance, and future studies are needed to replicate this finding and further elucidate the biological pathways underlying the association between BDNF and antipsychotics drug response. Expand
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