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Electrosurgical enucleation versus bipolar transurethral resection for prostates larger than 70 ml: a prospective, randomized trial with 5-year followup.
TLDR
For large volume benign prostatic hyperplasia PlasmaKinetic enucleation of the prostate is associated with less blood loss, shorter hospital stay and catheterization time than bipolar transurethral resection of the groin and seems to be superior at long-term followup with fewer reoperations necessary.
Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial.
TLDR
Among patients undergoing renal transplant, the use of autologous MSCs compared with anti-IL-2 receptor antibody induction therapy resulted in lower incidence of acute rejection, decreased risk of opportunistic infection, and better estimated renal function at 1 year.
Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and
TLDR
Transplantation of UC-MSC and aBM-MNC was safe and associated with moderate improvement of metabolic measures in patients with established type 1 diabetes, and the treatment was well tolerated.
Plasmakinetic enucleation of the prostate compared with open prostatectomy for prostates larger than 100 grams: a randomized noninferiority controlled trial with long-term results at 6 years.
TLDR
PKEP is a durable procedure with short- to long-term micturition improvement equivalent to OP and significantly lower perioperative morbidity and was noninferior to OP regarding Qmax at 1 yr postoperatively.
Mesenchymal-stem-cell-based experimental and clinical trials: current status and open questions
TLDR
This review aims at discussing the mechanisms of MSC-mediated immunomodulation and tissue repair and the related clinical trials, with special emphasis on factors that influence the efficiency of M SC-based therapy.
Mesenchymal Stem Cells Ameliorate Ischemia-Reperfusion-Induced Renal Dysfunction by Improving the Antioxidant/Oxidant Balance in the Ischemic Kidney
TLDR
MSC infusion significantly improved kidney function as indicated by lower urea and creatinine levels in the MSC compared to the vehicle group and at histological examination, the kidneys of MSC-treated rats showed a fairly normal morphology.
Autologous bone marrow mononuclear cell infusion and hyperbaric oxygen therapy in type 2 diabetes mellitus: an open-label, randomized controlled clinical trial.
TLDR
BM-MNC infusion for type 2 diabetes mellitus improves islet function and metabolic control, with mild adverse effects, and HOT does not synergize with BM-M NC infusion.
Alemtuzumab induction therapy in highly sensitized kidney transplant recipients.
TLDR
Alemtuzumab induction therapy for highly sensitized kidney transplant recipients is an effective and safe protocol yielding an acceptable acute rejection rate.
MiR-30a-5p frequently downregulated in prostate cancer inhibits cell proliferation via targeting PCLAF
Abstract MicroRNAs (miRNAs) have vastly expanded our view of RNA world in intracellular signal regulating networks. Here, we functionally characterized a normally highly expressed miRNA, miR-30a-5p
Umbilical cord mesenchymal stem cells for COVID‐19 acute respiratory distress syndrome: A double‐blind, phase 1/2a, randomized controlled trial
TLDR
UC‐MSC infusions are safe and could be beneficial in treating subjects with COVID‐19 ARDS and treatment was associated with significantly improved patient survival, SAE‐free survival, and time to recovery.
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