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- Rui-Ting Wen, Min Zhang, +5 authors Jian-hui Liang
- Alcoholism, clinical and experimental research
- 2012
BACKGROUND
Alcohol dependence is a complex psychiatric disorder demanding development of novel pharmacotherapies. Because the cyclic adenosine monophosphate (cAMP) signaling cascade has been… (More)
- Miao Ma, Jian-hui Liang, Min Guo, Yi Fan, Yilong Yin
- Appl. Soft Comput.
- 2011
- Jun-Xu Li, Qi Zhang, Jian-hui Liang
- Behavioural Brain Research
- 2004
Repetitive exposure to opioids elicits sensitization to its locomotor stimulating effects. Several lines of evidence have shown that the central GABAergic system is involved in behavioral… (More)
- Jian-hui Liang, Feng Chen, +5 authors Andrew J Lawrence
- Neuropharmacology
- 2006
GABA systems have been implicated as targets for ethanol at the cellular, molecular and behavioural level. The present study was designed to further examine the potential of the GABA(B) receptor as a… (More)
- Qi Zhang, Jun-Xu Li, Jiawei Zheng, Rui-Ke Liu, Jian-hui Liang
- European journal of pharmacology
- 2003
The relationship between opioid actions and L-type Ca(2+) channel blockers has been well documented. However, there is no report relevant to L-type Ca(2+) channel blockers and morphine sensitization,… (More)
- Jun-Xu Li, Wen-li Zhao, Jian-hui Liang
- Brain Research
- 2004
Effects of carbamazepine on behavioral sensitization to morphine in mice has been investigated. Mice treated daily for 7 days with morphine (10 mg/kg) induced behavioral sensitization. Carbamazepine… (More)
- Juan Luo, Li Jing, +4 authors Jian-hui Liang
- The international journal of…
- 2011
New protein synthesis has been implicated as necessary for long-lasting changes in neuronal function. Behavioural sensitization to a single exposure to addictive drugs is a form of neuroplasticity,… (More)
- Li Jing, Juan Luo, +6 authors Jian-hui Liang
- Neuroscience Letters
- 2011
Behavioural sensitization to a single morphine exposure has been considered to be a long-term form of behavioural plasticity associated with opioid addiction. Accumulated evidence has shown that… (More)
- Rui-Ting Wen, Wan-Yu Feng, Jian-hui Liang, Han Zhang
- Current pharmaceutical design
- 2015
The harmful effects caused by misuse of psychoactive substances have raised both medical and social problems. Substance dependence is a chronic relapsing disorder, which appears to involve… (More)
- Jian-hui Liang, I W Zheng
- Acta pharmacologica Sinica
- 2000
AIM
To study the effect of (+)-10, 11-dihydro-5-methyl-5H-dibenzo [a, d] cyclohepten-5, 10-imine maleate(dizocilpine maleate, MK-801) on the discriminative behavior of methamphetamine (MA).
METHODS… (More)