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The power consumption and operating frequency of the extended true single-phase clock (E-TSPC)-based frequency divider is investigated. The short-circuit power and the switching power in the E-TSPC-based divider are calculated and simulated. A low-power divide-by-2/3 unit of a prescaler is proposed and implemented using a CMOS technology. Compared with the(More)
By site-directed mutagenesis, six insulin residues related to the insulin-receptor interaction were grafted, partially or fully, onto the corresponding position of a recombinant amphioxus insulin-like peptide (ILP) that contained the A- and B-domains of the deduced amphioxus ILP. After fermentation, purification, and enzymatic cleavage, six insulin-like(More)
In this paper, compact ultra-wideband (UWB) bandpass filters with ultra-narrow dual- and quad-notched bands are proposed using the broadside-coupled microstrip/coplanar waveguide (CPW) structure. The multiple-modes UWB operation is obtained through the CPW detached-mode resonator (DMR) and broadside-coupled microstrip/CPW transition. To avoid the existing(More)
BACKGROUND Prostate cancer is a heterogeneous malignancy with outcome difficult to predict. Currently, there is an urgent need to identify novel biomarkers that can accurately predict patient outcome and improve the treatment strategy. The aim of this study was to investigate the methylation status of PCDH10 in serum of prostate cancer patients and its(More)
OBJECTIVE To investigate the clinical significance of cadherin 13 (CDH13) gene promoter methylation in the serum of patients with prostate cancer. METHODS This prospective study examined the methylation status of CDH13 in serum samples obtained from patients with primary prostate cancer and age-matched control subjects, using methylation-specific(More)
An empirical large-signal III-V field-effect transistor (FET) model has been developed. Three improved drain-source current (<i>I</i>-<i>V</i>) modeling equations capable of representing arbitrarily shaped transconductance (<i>Gm</i>) curves are proposed from level-1 to level-3. These models are characterized by the static dc and the multibias pulsed(More)
BACKGROUND Prostate cancer is a common malignancy in men, and inevitably some patients experience biochemical recurrence after radical prostatectomy. To date, there are no reliable predictors for prostate cancer recurrence, and novel predictors are urgently needed. PCDH10 (protocadherin-10) is a novel tumor suppressor gene, which is down-regulated by(More)
OBJECTIVES This study retrospectively evaluated the prognostic significance of downregulated protocadherin-10 (PCDH10) gene expression in bladder cancer. METHODS To evaluate the prognostic significance of downregulated PCDH10 protein levels, immunohistochemistry was used to assess the level of PCDH10 protein in surgically-resected formalin-fixed, paraffin(More)
BACKGROUND Aberrant methylation of protocadherin 17 (PCDH17) has been reported in several human cancers. However, the methylation status of PCDH17 in prostate cancer and its clinical significance remains unclear. The aim of this study was to investigate the methylation status of PCDH17 and its clinical significance in patients with prostate cancer after(More)
OBJECTIVE To explore the epidemic characteristics of vaginal douching, human immunodeficiency virus (HIV) and other sexually transmitted diseases(STD) among female sex workers (FSWs) in Yunnan province. METHODS FSWs were recruited to be investigated on their demographic data, drug abuse and sexual behavior, HIV/AIDS knowledge and procreation health(More)