Jian-an Yang

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The molecular mechanisms of the development and progression of bladder cancer are poorly understood. The objective of this study was to analyze the expression of Bmi-1 protein and its clinical significance in human bladder cancer. We examined the expression of Bmi-1 mRNA and Bmi-1 protein by RT-PCR and Western blot, respectively in 14 paired bladder cancers(More)
BACKGROUND There are more than 300,000 prosthetic heart valve replacements each year worldwide. These patients are faced with a higher risk of thromboembolic events after heart valve surgery and long-term or even life-long anticoagulative and antiplatelet therapies are necessary. Some severe complications such as hemorrhaging or rebound thrombosis can occur(More)
BACKGROUND & OBJECTIVE Renal angiomyolipoma (RMAL) is a benign renal tumor. The patients could be rechecked regularly or treated with operation. The result of operation is good. But the atypical cases are easy to be misdiagnosed. This study was to summarize our experiences of diagnosing and treating atypical RMAL. METHODS Clinical data of 22 atypical RMAL(More)
BACKGROUND & OBJECTIVE At present, the molecular mechanisms of development and progression of bladder cancer are still poorly understood. This study was to explore the expression and significance of Bmi-1 in bladder cancer, and analyze its correlations to clinicopathologic features and prognosis of bladder cancer. METHODS The expression of Bmi-1 protein(More)
OBJECTIVE To evaluate the value of human fatty acid binding protein (h-FABP) in predicting myocardial ischemia and injury in the perioperative period of cardiac surgery, we observed the dynamic changes of h-FABP in perioperative period of patients underwent coronary artery bypass grafting and ventricular septal defects repairing surgery, and evaluated the(More)
OBJECTIVE To investigate the protective effects of Cariporide on immature rabbit heart, and to search for the protective mechanism of the Na(+)/H(+) exchange inhibitor on immature rabbit hearts. METHODS New Zealand immature rabbits were randomly divided into two groups (n = 12 in each group). The isolated rabbit heart model was involved in this study. The(More)
AIM To observe the tissue-type plasminogen activator gene (t-PA) plasmid packaged with albumin nanoparticles crosslinked to albumin ultrasound microbubbles for targeting transfection to myocardium to prevent the graft thrombosis and vascular anastomotic restenosis after coronary bypass. METHODS A dog model of coronary bypass using the autoallergic(More)
OBJECTIVE To investigate the relationship between mild consciousness and mental disorders after arthroplasty and incomplete cerebral fat embolism. METHODS A retrospective analysis of 12 patients with incomplete cerebral fat embolism after arthroplasty was performed from June 2004 to December 2011. There were 5 males and 7 females,ranging in age from 36 to(More)
BACKGROUND & OBJECTIVE Latent pheochromocytoma (PHOE) is a rare disease with no symptom of hypertension, which is easily to be misdiagnosed before operation. There occurs dramatic fluctuations of blood pressure during surgical resection, and the risk of surgery for these patients is rather high. This study was to summarize our experiences in handling(More)
BACKGROUND & OBJECTIVE Since the histomorphology of adrenal tumor is very special, it is difficult to assess the malignancy of the tumors. This study was to explore the expression and clinical significance of Survivin and PTEN proteins in adrenal tumors. METHODS The expression of Survivin and PTEN in 116 specimens of adrenal tumors, including 39 cases of(More)
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