Jian Rong Li

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Recent analyses of RNA polymerase II (Pol II) revealed that Pol II is concentrated at the promoters of many active and inactive genes. NELF causes Pol II to pause in the promoter-proximal region of the hsp70 gene in Drosophila melanogaster. In this study, genome-wide location analysis (chromatin immunoprecipitation-microarray chip [ChIP-chip] analysis)(More)
The Ku heterodimer, conserved in a wide range of eukaryotes, plays a multiplicity of roles in yeast. First, binding of Ku, which is composed of a 70 kDa (Hdf1p) and an 80 kDa (Hdf2p) subunit [1-3], to double-strand breaks promotes non-homologous end-to-end joining of DNA [3]. Second, Ku appears to participate in DNA replication, regulating both the number(More)
BACKGROUND The cohesin complex mediates sister chromatid cohesion and regulates gene transcription. Prior studies show that cohesin preferentially binds and regulates genes that control growth and differentiation and that even mild disruption of cohesin function alters development. Here we investigate how cohesin specifically recognizes and regulates genes(More)
The ability of mammals to maintain a constant body temperature has proven to be a profound evolutionary advantage, allowing members of this class to thrive in most environments on earth. Intriguingly, some mammals employ bouts of deep hypothermia (torpor) to cope with reduced food supply and harsh climates [1, 2]. During torpor, physiological processes such(More)
Enteric protozoa are frequently found in snakes. Nevertheless, few studies regarding genetic characterization of these parasites have been carried out. We describe here the first molecular survey of protozoan pathogens from snakes in China and the first report on Enterocytozoon bieneusi genotyping in snakes in the world. Here, 240 fecal specimens were(More)
Soil salinization limits conventional agriculture since most food-based plant cultivars require low soil-sodium (Na+) levels for robust growth. Moreover, modern agricultural practices, especially in arid environments, can exacerbate soil salinization as belowground water sources utilized in irrigation are frequently tainted with salt. While salt tolerance(More)
Expansins are cell wall proteins involved in cell wall loosening and structural remodeling. In this study, we evaluated the transcript levels of 36 expansin genes in Populus tomentosa under heat stress (42 °C) and normal growth conditions (25 °C). One expansin gene, PttEXPA8, significantly up-regulated in leaves under heat stress, was cloned and transformed(More)
Wind, salt spray, and the proximity to the coastline significantly caused the variation of tree shape and dry mass density of Casuarina equisetifolia L. planted in coastal areas. Despite negative effects of exotic plants, they play an important role in the erosion control and the accumulation of wind-borne deposits in coastal areas. Identifying the adaptive(More)
The occurrence of fungal disease of crops requires a susceptible host, a virulent race, and a favourable environment. Environmental factors play crucial roles and ultimately determine epidemic of disease in host-pathogen interactions. However, the molecular basis of how fungi cope with environments still needs further research. Here, we characterized a(More)
This study aimed to investigate the characteristics of insulin resistance and β-cell secretion in healthy adolescents. A total of 124 adolescents with normal glucose tolerance (NGT) were divided according to BMI into normal weight (n=31; control), overweight (n=52) and obese (n=41) groups. Oral glucose tolerance tests were performed, and blood glucose (G 0(More)