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Intracerebroventricular transplantation of ex vivo expanded endothelial colony-forming cells restores blood-brain barrier integrity and promotes angiogenesis of mice with traumatic brain injury.
- Xin-tao Huang, Yongqiang Zhang, +5 authors Jian-Ning Zhang
- Journal of neurotrauma
- 12 December 2013
Endothelial progenitor cells (EPCs) play a key role in tissue repair and regeneration. Previous studies have shown a positive correlation between the number of circulating EPCs and clinical outcomes… Expand
Health-related quality of life in glioma patients in China
BackgroundHealth-related quality of life (HRQOL) has been increasingly emphasized in cancer patients. There are no reports comparing baseline HRQOL of different subgroups of glioma patients prior to… Expand
[Endoscopic endonasal transsphenoidal approach for pituitary adenomas].
- X. Zhang, Z. Fei, +7 authors W. Cao
- Zhonghua wai ke za zhi [Chinese journal of…
- 15 November 2006
OBJECTIVE To assess the clinical curative effect of the endonasal transsphenoidal approach for removing pituitary adenoma (PA) under neuroendoscope-assisted. METHODS There were 215 patients who had… Expand
Primary granulomatous hypophysitis: a case report and literature review.
Primary granulomatous hypophysitis (PGH) is a rarely occurred inflammatory disease of unknown etiology. We retrospective review a case of PGH treated by microsurgical transsphenoidal approach and… Expand
MicroRNA-566 activates EGFR signaling and its inhibition sensitizes glioblastoma cells to nimotuzumab
BackgroundEpidermal growth factor receptor (EGFR) is amplified in 40% of human glioblastomas. However, most glioblastoma patients respond poorly to anti-EGFR therapy. MicroRNAs can function as either… Expand
Membrane neovascularization and drainage of subdural hematoma in a rat model.
Studies on the pathophysiology of subdural hematomas (SDH) have been primarily focused on the acute phase and associated cortical injury, whereas the course of hematoma absorption remains poorly… Expand
HydroSoft coil versus HydroCoil for endovascular aneurysm occlusion study: a single center experience.
BACKGROUND AND PURPOSE The HydroCoil Embolic System (HES) was developed to reduce recurrences of aneurysms relative to platinum coils. But the HydroCoil Embolic System was characterized with many… Expand
Dexmedetomidine attenuates traumatic brain injury: action pathway and mechanisms
- Dong Wang, X. Xu, Yin-Gang Wu, Li Lyu, Z. Zhou, Jian-Ning Zhang
- Neural regeneration research
- 1 May 2018
Traumatic brain injury induces potent inflammatory responses that can exacerbate secondary blood-brain barrier (BBB) disruption, neuronal injury, and neurological dysfunction. Dexmedetomidine is a… Expand
Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury-associated coagulopathy in mice.
Cardiolipin (CL) is an anionic phospholipid located exclusively in the mitochondrial inner membrane. Its presence in blood indicates mitochondrial damage and release from injured cells. Here, we… Expand
Delivery of a peptide-drug conjugate targeting the blood brain barrier improved the efficacy of paclitaxel against glioma
The challenge of effectively delivering therapeutic agents to the brain has created an entire field of active research devoted to overcoming the blood brain barrier (BBB) and efficiently delivering… Expand