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Microbial bioconversion of the chemical components in dark tea.
Bioactive lignans from Peperomia duclouxii.
Six new lignans (1-6), along with 14 known compounds, were obtained from Peperomia duclouxii and showed anti-inflammatory activity using an ICAM-1 assay (induction of the intercellular adhesion molecule-1), stimulated by IL-1alpha and TNF-alpha.
Qualitative and quantitative analysis of lipo-alkaloids and fatty acids in Aconitum carmichaelii using LC-MS and GC-MS.
The positive correlation betweenfree fatty acids and LAs in A. carmichaelii indicated that the types and contents of LAs were influenced by free fatty acids.
Aspirin Reduces Colorectal Tumor Development in Mice and Gut Microbes Reduce its Bioavailability and Chemopreventive Effects.
Aspirin reduces development of colorectal tumors in APCmin/+ mice and mice given azoxymethane and DSS, depending on the presence of intestinal microbes, and reduces its chemopreventive effects in mice.
Dibenzylbutyrolactone and dibenzylbutanediol lignans from Peperomia duclouxii.
Nine new lignans (1-9) were obtained from an ethyl acetate extract of the whole plants of Peperomia duclouxii, and the absolute structures were elucidated as 2S,3S from their optical rotations and by chemical transformations.
Integrated Meta-omics Approaches To Understand the Microbiome of Spontaneous Fermentation of Traditional Chinese Pu-erh Tea
An integrated meta-omics approach was used to study the microbiome in the fermentation of pu-erh tea, which is a well-known Chinese fermented food with a special flavor and healthful benefits, and demonstrated microbiota in fermentation and their function in the production of enzymes related to the degradation of polysaccharides, and metabolism of phenolic compounds, resulting in changes in metabolite contents and the quality of Pu-erH tea.
Bioactive secolignans from Peperomia dindygulensis.
Thirteen secolignans, including eight new ones (1-8), were isolated from the EtOAc extract of Peperomia dindygulensis and showed inhibitory activity on induction of the intercellular adhesion molecule-1 (ICAM-1).
Bioactive polyketides from Peperomia duclouxii.
Four new compounds (1-4) were isolated along with 16 known compounds from whole plants of Peperomia duclouxii, showing moderate to weak inhibitory activity on the induction of the intercellular adhesion molecule-1 (ICAM-1) in the presence of IL-1alpha or TNF-alpha.
Exploration and correlation analysis of changes in Krebs von den Lungen-6 levels in COVID-19 patients with different types in China.
KL-6 could be an indicator to evaluate the progression of COVID-19, which is parallel to the level of lung injury and inflammation in patients, and it can also reflect the pulmonary ventilation function.
Rapid identification of new minor chemical constituents from Smilacis Glabrae Rhizoma by combined use of UHPLC-Q-TOF-MS, preparative HPLC and UHPLC-SPE-NMR-MS techniques.
The combination of UHP LC-Q-TOF-MS, preparative HPLC and UHPLC-SPE-NMR-MS techniques is a quick and effective approach for finding new minor constitutes from herbs.