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Ropivacaine impairs mitochondrial biogenesis by reducing PGC-1α.
- Zejun Niu, Jiaming Tang, Yueyi Ren, Wei Feng
- Biochemical and biophysical research…
- 2 October 2018
Supporting evidence is provided that mitochondrial impairment is a key event in ropivacaine-mediated neurotoxicity, and the reduction of PGC-1α and its downstream signals are likely the molecular mechanism behind its cellular toxicity. Expand
[A patient with acute mononuclear leukemia 9 months after bone marrow necrosis].