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The two-dipole model of theta generation in hippocampal CA1 suggests that the inhibitory perisomatic theta dipole is generated by local GABAergic interneurons. Various CA1 interneurons fire preferentially at different theta phases, raising the question of how these theta-locked interneurons contribute to the generation of theta oscillations. We here(More)
Safflower has long been used to treat cerebrovascular diseases in China. We previously reported that kaempferol derivatives of safflower can bind DJ-1, a protein associated with Parkinson's disease (PD), and flavonoid extract of safflower exhibited neuroprotective effects in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of PD. In this(More)
—Text detection and recognition is a challenging problem in document analysis due to the presence of the unpredictable nature of video texts, such as the variations of orientation, font and size, illumination effects, and even different 2D/3D text shadows. In this paper, we propose a novel horizontal and vertical symmetry feature by calculating the gradient(More)
—Achieving good accuracy for text detection and recognition is a challenging and interesting problem in the field of video document analysis because of the presences of both graphics text that has good clarity and scene text that is unpredictable in video frames. Therefore, in this paper, we present a novel method for classifying graphics texts and scene(More)
Parkinson's disease (PD) is a major age-related neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra par compacta (SNpc). Rotenone is a neurotoxin that is routinely used to model PD to aid in understanding the mechanisms of neuronal death. Safflower (Carthamus tinctorius. L.) has long been used to treat(More)
  • Ning Wang, Wen Jing Yi, +7 authors Rui Zhang
  • 2017
Pancreatic beta cells are very sensitive to oxidative stress, which is one of the major causes of cell damages in diabetes. Growing interest has focused on the development of effective therapeutics to protect pancreatic cells from oxidative stress and searching for potentially protective antioxidants for treating diabetes. Apigenin, a plant-derived(More)
Lateral and medial parts of entorhinal cortex (EC) convey nonspatial 'what' and spatial 'where' information, respectively, into hippocampal CA1, via both the indirect EC layer 2→ hippocampal dentate gyrus→CA3→CA1 and the direct EC layer 3→CA1 paths. However, it remains elusive how the direct path transfers distinct information and contributes to hippocampal(More)
Previous studies of egg drop syndrome virus (EDSV) is restricted to serological surveys, disease diagnostics, and complete viral genome analysis. Consequently, the infection characteristics and entry routes of EDSV are poorly understood. Therefore, we aimed to explore the entry pathway of EDSV into duck embryonic fibroblast (DEF) cells as well as the(More)
Text detection and recognition in video is challenging due to the presence of different types of texts, namely, graphics (video caption), scene (natural text), 2D, 3D, static and dynamic texts. Developing a universal method that works well for all these types is hard. In this paper, we propose a novel method for classifying graphics-scene and 2D-3D texts in(More)
ETHNOPHARMACOLOGICAL RELEVANCE Xiaoer Chaigui Tuire Oral Liquid (XCTOL) is a popular Chinese herbal formula. It is used to treat exogenous fever in children by inducing diaphoresis and clearing interior heat. AIM OF THE STUDY To evaluate the acute and sub-chronic toxicity of XCTOL in mice and rats, respectively. MATERIALS AND METHODS In the acute(More)