Jiali Feng

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The phosphodiesterase 4B (PDE4B) is a candidate susceptibility gene for schizophrenia (SCZ), interacting with DISC1, a known genetic risk factor for SCZ. To examine if variants within PDE4B gene are associated with SCZ in Northwestern Han Chinese, and if these effects vary in gender-specific subgroup, we analyzed 20 SNPs, selected from previous studies and(More)
SLC1A2 is reported to be responsible for the majority of glutamate uptake, which has a crucial role in neural development and synaptic plasticity, and a disturbance in glutamatergic transmission has been suggested to be involved in the pathophysiology of schizophrenia (SCZ) and cognition. To evaluate the relationship of common variants within SLC1A2 with(More)
Memory modulation is implemented through many different factors, such as the dopaminergic system and ovarian hormones. Alterations of these factors may cause memory behavior changes. In the current study, dopamine D3 receptor mutant (D3(-/-)) female mice and their wild-type (WT) controls were used and randomly assigned to ovariectomized (OVX) and(More)