Jiajia Yang

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Fitts' law robustly predicts the time required to move rapidly to a target. However, it is unclear whether Fitts' law holds for visually guided actions under visually restricted conditions. We tested whether Fitts' law applies under various conditions of visual restriction and compared pointing movements in each condition. Ten healthy participants performed(More)
Maternal nutrition plays a critical role in physical growth and neurobehavior of offspring. The aim of this study was to assess the nature of maternal undernutrition on the physical growth and neurobehavior of newborn male and female rat pups. To attain this aim, a model of maternal 50% food restriction (FR50) was induced in Wistar rats. After parturition,(More)
The characteristics of raised-line drawing discrimination can be defined as the sum of the discriminability of the length, curvature, and angles of the edges. The size of the angle between two edges constitutes an important feature of these tactile stimuli. In the first experiment, five standard angles (30 degrees, 60 degrees, 90 degrees, 120 degrees, and(More)
Vascular endothelial growth factor (VEGF) has recently been proved to be a potential therapeutic drug in ischemic disorders depending on the dose, route and time of administration, especially in focal cerebral ischemia. Whether VEGF could exert protection in a long-term total cerebral ischemic model is still uncertain, and the cellular mechanism has not(More)
Intra-active touch (IAT) is a process that involves a body part doing the touching (active touch [AT]) and another body part being touched (passive touch [PT]) simultaneously. The brain representation related to IAT is still unclear. A total of 23 subjects carried out angle discrimination under PT, AT and IAT conditions with functional magnetic resonance(More)
Chinese is a logographic language system that differs from alphabetic languages, and some of the neurocognitive mechanisms underlying Chinese logographic reading also differ from those underlying alphabetic word reading. However, whether education level effects the neural activation associated with logographic processing of Chinese is still unknown. In the(More)
The scandal of melamine-contamination has not been quite blown out, since the toxicity of melamine continues to raise concerns for public health. It has been well known that fetus and infant periods play the most important roles in brain development, whereas little has been done on the harmful effects of melamine on the center nervous system (CNS) of(More)
There is a need to differentiate between patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) from normal-aged controls (NC) in the field of clinical drug discovery. In this study, we developed a tactile angle discrimination system and examined whether the ability to discriminate tactile angle differed between patients with MCI and AD(More)
It is well known that the neuronal effects of vascular endothelial growth factor (VEGF) include modulating learning and memory, plasticity of mature neurons, and synaptic transmission in addition to neurogenesis. However, there is conflicting evidence particularly of its role in the regulation of excitatory synaptic activity. In this study, application of(More)