Jiabin Liu

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In developing B lymphocytes, a successful V(D)J heavy chain (HC) immunoglobulin (Ig) rearrangement establishes HC allelic exclusion and signals pro-B cells to advance in development to the pre-B stage. A subsequent functional light chain (LC) rearrangement then results in the surface expression of IgM at the immature B cell stage. Here we show that(More)
Marginal zone (MZ) B cells play an important role in the clearance of blood-borne bacterial infections via rapid T-independent IgM responses. We have previously demonstrated that MZ B cells respond rapidly and robustly to bacterial particulates. To determine the MZ-specific genes that are expressed to allow for this response, MZ and follicular (FO) B cells(More)
Minimal test cost attribute reduction is an important issue in cost-sensitive learning. Recently, an information gain based heuristic algorithm has been designed to this problem. However, the algorithm does not often find the optimal solution. In this paper, we develop an ant colony optimization algorithm to deal with this problem. First, the attribute set(More)
Test cost is often required to obtain feature values of an object. When this issue is involved, people are often interested in schemes minimizing it. In many data mining applications, due to economic, technological and legal reasons , it is neither possible nor necessary to obtain a classifier with 100% accuracy. There may be an industrial standard to(More)
In many machine learning applications, we need to pay test cost for each data item. Due to limited money and/or time, we also have a constraint on the total test cost. This issue have been recently formalized as the optimal sub-reduct with test cost constraint problem. An information gain based heuristic algorithm has been proposed to deal with it. In this(More)
Development of the fruit fly Drosophila depends in part on epigenetic regulation carried out by the concerted actions of the Polycomb and Trithorax group of proteins, many of which are associated with histone methyltransferase activity. Mouse PTIP is part of a histone H3K4 methyltransferase complex and contains six BRCT domains and a glutamine-rich region.(More)
Premature ovarian failure (POF) is a long-term adverse effect of chemotherapy treatment. However, current available treatment regimens are not optimal. Emerging evidence suggests that bone marrow-derived mesenchymal stem cells (BMSCs) could restore the structure and function of injured tissues, but the homing and restorative effects of BMSCs on chemotherapy(More)
OBJECTIVES To evaluate the clinical value of noise-based tube current reduction method with iterative reconstruction for obtaining consistent image quality with dose optimization in prospective electrocardiogram (ECG)-triggered coronary CT angiography (CCTA). MATERIALS AND METHODS We performed a prospective randomized study evaluating 338 patients(More)
The direct wave and clutter wave cancellation is a key procedure for noise FM-CW (frequency-modulated continuous-wave) radar. Frequency-domain Block LMS (FBLMS) adaptive filters have better performance of clutter (include the direct wave) cancellation in low computational complex. In practical system, however, the chosen of step-size and the tap length of(More)