Jia-zhi Yan

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OBJECTIVE To evaluate the mechanical response of L3-L4 segment after posterior interfixation with a transpedicle screw system. METHODS Spiral CT machine was used to conduct continuous parallel scan on the L3-L4 section of a 40-year-old healthy male Chinese. The image data thus obtained were introduced into MIMICS software to reconstruct the 2-D data into(More)
OBJECTIVE To explore the best surgical fusion level for adolescent idiopathic scoliosis (AIS) of PUMC II d(2) with finite element model (FEM). METHODS FEM (T(5)-S) of PUMC II d(2) idiopathic scoliosis was used to simulate upper thoracic curve, lower lumbar curve and double curve fusion manners. The pedicle of concave vertebral arch received 50, 100 and(More)
OBJECTIVE To investigate the association between Trp2 allele polymorphism with degenerative disc disease (DDD) in a Chinese Han population. METHODS A total of 125 DDD patients (58 males and 67 females, 51.8 +/- 7.6 years old), and 125 controls matched in sex and age (63 males and 62 females, 45.3 +/- 8.3 years old) were recruited in the case-control(More)
OBJECTIVE To study the relationship between the fulcrum bending flexibility (FBF) and correction rate (CR) of adult idiopathic scoliosis, and to explore the ability of FBF to assess the correction effect in relation to fulcrum bending flexibility. METHODS 69 patients with adult idiopathic scoliosis with structural curves at thoracic or lumbarthoracic(More)
BACKGROUND Adjacent segment degeneration (ASD) following lumbar fusion has been well documented in recent years. However, the pathogenesis of ASD is not clear. To investigate this issue, we established a finite element model of segments L2-L5, simulated a single-segment posterior fixation in L3-L4 and investigated the stress variation and the effects of the(More)
OBJECTIVES To study the stress distribution of the adjacent different grades of disc degeneration underwenting unilateral laminectomy and discectomy surgery using non-linear finite element analysis. METHODS Based on the lumbar CT scans, the finite element model (FEM) of lumbar spinal segment (L3-L5) was established. According to L3-L4 intervertebral disc(More)
OBJECTIVE To investigate the mechanical changes of the degenerated lumbar disc with finite element analysis. METHODS A three dimensional finite element model of a human lumbar spine at the L3-L4 disc was established by the software MIMICS and ABAQUS based on computer tomography images. Degeneration was modeled by changes in geometry and material(More)
OBJECTIVE To observe the biomechanic properties of sciatic nerve at the suture site in rats following repairing. METHODS The right sciatic nerves of 40 white Sprague-Dawley 300-350 gm rats were exposed, cut and then repaired with 10-0 nylon sutures, laced in the epineurium. 0, 1, 3, 6 weeks after operation, the tensile strength of the sciatic nerves were(More)
OBJECTIVE To build a 3D finite element model of whole lumbar spine and verify its efficiency and analyze the biomechanical change of L3-4 motion segment. METHODS L1-L5 segment data were obtained from computed tomography (CT) scans of the lumbar spine of a 40-year-old man with no abnormal findings. A three-dimensional finite element model of the human(More)
BACKGROUND Small animal models that can mimic degenerative disc disease (DDD) are commonly used to examine DDD progression. However, assessments such as histological studies and macroscopic measurements do not allow for longitudinal studies because they can only be completed after the animal is sacrificed. Dynamic contrast-enhanced MRI (DCE-MRI) may provide(More)