Jia Sen Huo

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Osthole, a bioactive simple coumarin derivative extracted from many medicinal plants such as Cnidium monnieri (L.) Cusson, exerts a broad spectrum of pharmacological activities and is considered to have potential therapeutic applications. The aim of this study was to investigate the potential neuroprotective role of osthole against ischemic injury in vitro,(More)
In this paper, we propose a high-speed parallel 128 bit multiplier for Ghash Function in conjunction with its FPGA implementation. Through the use of Verilog the designs are evaluated by using Xilinx Vertax5 with 65nm technic and 30,000 logic cells. The highest throughput of 30.764Gpbs can be achieved on virtex5 with the consumption of 8864 slices LUT. The(More)
Psoriasis is a one of the most common chronic skin diseases, which affects 0.6–4.8 % of the general population. Amentoflavone (AMF) belongs to the biflavonoid class of flavonoids, possessing various biological effects, such as anti-inflammatory, antioxidant, and anti-apoptotic effects. In the present study, we aimed to investigate the effect of AMF on(More)
To investigate potential associations between carotid artery stenosis and cognitive impairment among patients with acute ischemic stroke and to provide important clinical implications. We measured the degree of carotid artery stenosis and recorded the Mini-Mental State Examination score (MMSE) at admission in 3116 acute ischemic stroke patients. The(More)
Wireless Capsule Endoscopy (WCE) is a promising new solution for gastrointestinal disease detection, which is able to view the entire gastrointestinal tract without pain. Since there are more than 50,000 frames in one WCE video from each test, the automatic computer-aided technique is highly demanded to remove the redundant frames while remaining the(More)
Paraplegia caused by spinal cord ischemia is a severe complication following surgeries in the thoracic aneurysm. HMGB1 has been recognized as a key mediator in spinal inflammatory response after spinal cord injury. Electroacupuncture (EA) pretreatment could provide neuroprotection against cerebral ischemic injury through inhibition of HMGB1 release.(More)
To investigate the anti-human epidermal squamous-cell carcinoma A431 cell proliferative fraction of Euphorbia fischeriana Steud. and to determine chamaejasmine B content in the fraction. Anti-A431 cell proliferative activity of various Euphorbia fischeriana Steud. fractions, which were extracted using Steud. HPLC determination of chamaejasmine B content in(More)
Previous research indicates that microRNA-25 (miR-25) regulates carcinogenesis and the progression of various cancers, but the role of miR-25 in melanoma remains unclear. We observed that miR-25 was significantly upregulated in melanoma cell lines and tissue samples. Downregulation of miR-25 markedly suppressed invasion and proliferation of melanoma cells(More)
The glyceraldehyde-3-phosphate dehydrogenase (GAPDH)/Siah1 signaling pathway has been recognized as a sensor of nitric oxide (NO). It is associated with a variety of injurious conditions, suggesting its therapeutic potential for spinal cord injury (SCI). Sivelestat sodium (SIV), a neutrophil elastase (NE) inhibitor initially used to treat acute lung injury,(More)
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