Jia Jun Chen

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Digested proteins are mainly absorbed as small peptides composed of two or three amino acids. The intestinal absorption of small peptides is mediated via only one transport system: the proton-coupled peptide transporter-1 (PepT1) encoded from the soluble carrier protein Slc15a1. In mammals, intestinal expression of PepT1/Slc15a1 oscillates during the daily(More)
For the investigation of intracerebral dopamine metabolism, 6-[18F]fluoro-l-m-tyrosine (FmT) has been proposed as an alternative tracer that, unlike 6-[18F]fluoro-l-dopa, is not subjected to O-methylation. We have studied the time course of FmT and its labelled metabolites in plasma after intravenous injection into humans, employing a method that we have(More)
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