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The number of adipocytes is relevant to the extent of differentiation from pluripotent stem cells into pre-adipocytes, whereas the size of adipocytes relates to the extent of differentiation from pre-adipocytes into mature fat cells and the accumulation of triglyceride. Investigation of the molecular regulatory mechanism of adipocyte differentiation is not(More)
BACKGROUND Homocysteine is known to be an independent risk factor for congenital heart disease (CHD). Methionine synthase reductase (MTRR) is essential for the adequate remethylation of homocysteine, which is the dominant pathway for homocysteine removal during early embryonic development. METHODS AND RESULTS Here, we report that the c.56+781 A>C(More)
Homocysteine is an independent risk factor for various cardiovascular diseases. There are two ways to remove homocysteine from embryonic cardiac cells: remethylation to form methionine or transsulfuration to form cysteine. Cystathionine β-synthase (CBS) catalyzes the first step of homocysteine transsulfuration as a rate-limiting enzyme. In this study, we(More)
BACKGROUND Osteoporosis is one of the systemic features of COPD. A correlation between the emphysema phenotype of COPD and reduced bone mineral density (BMD) is suggested by some studies, however, the mechanisms underlying this relationship are unclear. Experimental studies indicate that IL-1β, IL-6 and TNF-α may play important roles in the etiology of both(More)
BACKGROUND Ventricular diastolic dysfunction in patients with repaired tetralogy of Fallot (TOF) may affect atrial mechanics. This study aimed to explore right atrial (RA) and left atrial (LA) mechanics in repaired TOF patients and their relationship with ventricular diastolic function. METHODS Fifty-four patients (36 males), aged 17.8 ± 8.3 years, who(More)
A better understanding of the molecular mechanisms that regulate adipose tissue-derived stromal cell (ADSC) differentiation could provide new insight into some adipose-tissue-related disease. The differentiation of ADSCs into adipocytes is a complex physiological process that includes clonal expansion, growth arrest, and terminal differentiation. Here the(More)
Methyl jasmonate (MeJA) is one of most abundant scent compounds in Cymbidium ensifolium flowers. In this study, the emission of MeJA and its regulation mechanism were investigated. Our results showed that emission of MeJA in C. ensifolium flowers was controlled developmentally and rhythmically. It occurred in a tissue-specific manner, and high MeJA emission(More)
One-dimensional and two-dimensional fast algorithms for realizing the block inverse jacket transform with size of N=2<sup>k</sup> and 3 <sup>k</sup> are proposed. The fast algorithms are based on sparse matrix factorization of the block inverse jacket matrix and recursive form of the Kronecker products of identity matrices and successively lower-order block(More)