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BACKGROUND Homocysteine is known to be an independent risk factor for congenital heart disease (CHD). Methionine synthase reductase (MTRR) is essential for the adequate remethylation of homocysteine, which is the dominant pathway for homocysteine removal during early embryonic development. METHODS AND RESULTS Here, we report that the c.56+781 A>C(More)
Immunocytes, mainly neutrophils and monocytes, exhibit an intrinsic homing property, enabling them to migrate to sites of injury and inflammation. They can thus act as Trojan horses carrying concealed drug cargoes while migrating across impermeable barriers to sites of disease, especially the blood-brain barrier (BBB). In this study, to target circulating(More)
One-dimensional and two-dimensional fast algorithms for realizing the block inverse jacket transform with size of N=2<sup>k</sup> and 3 <sup>k</sup> are proposed. The fast algorithms are based on sparse matrix factorization of the block inverse jacket matrix and recursive form of the Kronecker products of identity matrices and successively lower-order block(More)
We design multilevel coding (MLC) with a semi-bit interleaved coded modulation (BICM) scheme based on low density parity check (LDPC) codes. Different from the traditional designs, we joined the MLC and BICM together by using the Gray mapping, which is suitable to transmit the data over several equivalent channels with different code rates. To perform well(More)
Nitrogen (N) is an essential mineral element for plant growth processes, and its availability severely affects the productivity of plants, especially trees. MicroRNAs (miRNAs) are a class of non-coding RNAs approximately 21 nucleotides in length that play important roles in plant growth, development and stress responses. To identify Populus miRNAs and their(More)
A better understanding of the molecular mechanisms that regulate adipose tissue-derived stromal cell (ADSC) differentiation could provide new insight into some adipose-tissue-related disease. The differentiation of ADSCs into adipocytes is a complex physiological process that includes clonal expansion, growth arrest, and terminal differentiation. Here the(More)