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Anthropometric data on the proximal tibia and distal femur of 172 normal knees (94 male knees, 78 female knees) were obtained using three dimensional computer tomographic measurements. We measured the tibial mediolateral (tML) and tibial anteroposterior (tAP) dimension in resected proximal tibia surface, femoral mediolateral (fML) and femoral(More)
An efficient and reliable a posteriori error estimate is derived for linear parabolic equations which does not depend on any regularity assumption on the underlying elliptic operator. An adaptive algorithm with variable time-step sizes and space meshes is proposed and studied which, at each time step, delays the mesh coarsening until the final iteration of(More)
Celsr3 and Fzd3, members of "core planar cell polarity" (PCP) genes, were shown previously to control forebrain axon guidance and wiring by acting in axons and/or guidepost cells. Here, we show that Celsr2 acts redundantly with Celsr3, and that their combined mutation mimics that of Fzd3. The phenotypes generated upon inactivation of Fzd3 in different(More)
BACKGROUND AND AIM The aim of this study was to explore the distribution and clinical characteristics of four subtypes of irritable bowel syndrome (IBS) based on Rome III criteria in Chinese. METHODS A total of 754 consecutive IBS outpatients from three tertiary hospitals in China were included. Diagnostic criteria were based on Rome II or Rome III. (More)
Macroalgae have received much attention for heavy metal removal in treatment of domestic wastewater. In this report, the uptake capacity of a common freshwater green alga, Cladophora fracta, for heavy metal ions (copper, zinc, cadmium, and mercury) was evaluated. The equilibrium adsorption capacities were 2.388 mg Cu2+, 1.623 mg Zn2+, 0.240 mg Cd2+, and(More)
Nitzschia ZJU1, which originated from the diatom Nitzschia sp. (ash free dry weight of biomass was 0.12 g L−1 and its lipid content was 13.34 %) after 60Co-γ ray irradiation and domestication at high-salinity, was re-mutated by 137Cs-γ irradiation to increase lipid productivity. The lipid yields of the new mutants Nitzschia ZJU2 and Nitzschia ZJU3, which(More)
BACKGROUND Mutations in the THAP1 gene have recently been identified as the cause of DYT6 primary dystonia. However, the changes in THAP1 gene function and in the microstructure of brain white matter have not been well-characterized. METHODS Four different mutations of THAP1 expression (clones F22fs71X, C54F, F25fs53X, and L180S) were transfected into(More)
Nedd1 is a new member of the gamma-tubulin ring complex (gammaTuRC) and targets the gammaTuRC to the centrosomes for microtubule nucleation and spindle assembly in mitosis. Although its role is known, its functional regulation mechanism remains unclear. Here we report that the function of Nedd1 is regulated by Cdk1 and Plk1. During mitosis, Nedd1 is firstly(More)
BACKGROUND Endoscopic retrograde appendicitis therapy (ERAT) is a new procedure for the treatment of acute uncomplicated appendicitis. The aim of the study was to review the clinical outcomes of ERAT and further examine its effectiveness and safety. METHODS The study was performed on patients who underwent ERAT for acute uncomplicated appendicitis at(More)
OBJECTIVE The aim of this study was to evaluate several polymer carriers with regard to the bioavailability enhancement of bifendate solid dispersions (SD) prepared by hot-melt extrusion (HME) and select the most appropriate polymer carrier. METHODS Solid dispersions containing bifendate in different polymers, including Plasdone(®) S-630, Eudragit(®) EPO(More)