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An efficient and reliable a posteriori error estimate is derived for linear parabolic equations which does not depend on any regularity assumption on the underlying elliptic operator. An adaptive algorithm with variable time-step sizes and space meshes is proposed and studied which, at each time step, delays the mesh coarsening until the final iteration of(More)
Celsr3 and Fzd3, members of "core planar cell polarity" (PCP) genes, were shown previously to control forebrain axon guidance and wiring by acting in axons and/or guidepost cells. Here, we show that Celsr2 acts redundantly with Celsr3, and that their combined mutation mimics that of Fzd3. The phenotypes generated upon inactivation of Fzd3 in different(More)
Nitzschia ZJU1, which originated from the diatom Nitzschia sp. (ash free dry weight of biomass was 0.12 g L−1 and its lipid content was 13.34 %) after 60Co-γ ray irradiation and domestication at high-salinity, was re-mutated by 137Cs-γ irradiation to increase lipid productivity. The lipid yields of the new mutants Nitzschia ZJU2 and Nitzschia ZJU3, which(More)
Macroalgae have received much attention for heavy metal removal in treatment of domestic wastewater. In this report, the uptake capacity of a common freshwater green alga, Cladophora fracta, for heavy metal ions (copper, zinc, cadmium, and mercury) was evaluated. The equilibrium adsorption capacities were 2.388 mg Cu2+, 1.623 mg Zn2+, 0.240 mg Cd2+, and(More)
Atypical cadherin Celsr3, a regulator of planar cell polarity, is critical for the development of the axonal blueprint. We previously showed that expression of Celsr3 is necessary to establish forebrain connections such as the anterior commissure and thalamocortical and corticospinal tracts. The requirement for Celsr3 during hippocampal wiring and its(More)
Brachial plexus injury (BPI) and experimental spinal root avulsion result in loss of motor function in the affected segments. After root avulsion, significant motoneuron function is restored by re-implantation of the avulsed root. How much this functional recovery depends on corticospinal inputs is not known. Here, we studied that question using Celsr3|Emx1(More)
Mutations in the THAP1 gene were recently identified as the cause of DYT6 primary dystonia. More than 40 mutations in this gene have been described in different populations. However, no previous report has identified sequence variations that affect the transcript process of the THAP1 gene. In addition, the mutation frequency in Chinese early-onset primary(More)
Chaotic modulation is a useful technique for spread spectrum communication. In this paper, an on-line adaptive chaotic demodulator based on a radial-basis-function (RBF) neural network is proposed and designed. The demodulator is implemented by an on-line adaptive learning algorithm, which takes advantage of the good approximation capability of the RBF(More)
BACKGROUND Dystonia is defined as the presence of sustained involuntary muscle contractions, often leading to abnormal posture and movement. DYT1 is caused by a mutation in the TOR1A gene, whilst mutations in THAP1 gene have been identified as responsible for DYT6. The relative frequency and phenotype differences between DYT1 and DYT6 amongst Chinese(More)