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BACKGROUND There is increasing evidence that cancers contain their own stem-like cells, and particular attention has been paid to one subset of cancer-stem cells termed side population (SP). Stem cells under normal physical conditions are tightly controlled by their microenvironment, however, the regulatory role of the microenvironment surrounding cancer(More)
OBJECTIVE To establish a new model of cardiac arrest (CA) in rats by transcutaneous electrical epicardium stimulation. METHODS Two acupuncture needles connected to the anode and cathode of a stimulator were transcutaneously inserted into the epicardium as electrodes. The stimulating current was steered to the epicardium and the stimulation was maintained(More)
AIM To investigate variation of hydrogen sulfide (H2S) in serum of rats after cardiopulmonary resuscitation (CPR) and explore its pathophysiological role in CPR. METHODS The 30 male SD rats were randomly divided into control group (n=6) and experimental group (n=24), then models of cardiac arrest (CA) were established in rats of experimental group by(More)
OBJECTIVE To investigate the protective effect of reactive oxygen species (ROS) scavenger, N-acetyl-L-cysteine (NAC), against H9c2 cardiomyocytes from injuries induced by chemical hypoxia. METHODS H9c2 cells were treated with cobalt chloride (CoCl2), a chemical hypoxia-mimetic agent, to establish the chemical hypoxia-induced cardiomyocyte injury model.(More)
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