Ji-xin Wang

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OBJECTIVE To observe the change in expression of Toll-like receptor 4 (TLR4) of splenic macrophage in patients with hypersplenism due to portal hypertension (PH), and investigate the role of TLR4 of splenic macrophage in hypersplenism. METHODS Splenectomy was performed on 20 patients with hypersplenism due to PH (hypersplenism group) and 6 patients with(More)
An ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) approach was developed and validated for the determination of ginkgolide L (GL) in rat plasma and tissues using diazepam as internal standard (IS). Detection was performed on a triple quadrupole MS system using multiple reaction monitoring (MRM) mode in(More)
Nowadays, network pharmacology-based methods were increasing proposed to screen synergistic or combinatorial compounds from herbal medicines (HMs), while these researches mainly focused on structural prediction or experiment-based interaction between single compound and target protein. The proportion of each chemical in the nature and their metabolic(More)
This paper analyzed the potential grads model (PGM) based quasi-dynamic method (QDM) used to solve the problem of emergent evacuation in complex building channels. The method is used to indicate the optimized or hypo-optimized route for evacuation, which makes the whole of the escapee evacuate in shortest distance, lowest resistance and best time. The(More)
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