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Identification of key miRNAs and genes associated with stomach adenocarcinoma from The Cancer Genome Atlas database
TLDR
Differential expression of the mature form of miRNAs and genes including ADAM12, ACAN, HOXC11 and MMP11 and calcium and bile secretion signaling pathways may play important roles in the development of STAD. Expand
Safety and efficacy of total parenteral nutrition versus total enteral nutrition for patients with severe acute pancreatitis: a meta-analysis
TLDR
This meta-analysis indicates that TEN is safer and more effective than TPN for patients with SAP, and when both TEN and TPN have a role in the management of SAP, T EN is the preferred option. Expand
hnRNPK promotes gastric tumorigenesis through regulating CD44E alternative splicing
TLDR
The upregulation of hnRNPK activates the expression of the splicing regulator SRSF1 by binding to the first motif upstream the start codon, thereby increasing splicing activity and expression of an oncogenic CD44 isoform,CD44E (has additional variant exons 8 to 10, CD44v8-v10). Expand
Hsa-miR-202-3p, up-regulated in type 1 gastric neuroendocrine neoplasms, may target DUSP1
AIM To detect abnormal microRNA (miRNA) expression in type 1 gastric neuroendocrine neoplasms (g-NENs) and find potential target genes. METHODS Tumour tissues from patients with type 1 g-NENs wereExpand
[Subtype classification and clinicopathological characteristics of gastric neuroendocrine neoplasms: an analysis of 241 cases].
  • Pan Zhang, Yu Zhang, +9 authors H. Tan
  • Medicine
  • Zhonghua wei chang wai ke za zhi = Chinese…
  • 25 November 2016
TLDR
Subtype classification of gastric NEN is very significant for making therapeutic decisions and prognostic evaluation, while those of type III( and type IIII( have poor prognosis, and those of types I, II and III have the worst prognosis. Expand
Screening key long non-coding RNAs in early-stage colon adenocarcinoma by RNA-sequencing.
TLDR
Compared with colonic intraepithelial neoplasia, differentially expressed lncRNAs in early-stage COAD were obtained by RNA-sequencing and DEmiRNA-DElnc RNA-DEmRNA interaction analysis and functional annotation were performed. Expand
Screening key genes and miRNAs in early-stage colon adenocarcinoma by RNA-sequencing
TLDR
Ten differentially expressed genes and four DEmiRNAs may be involved in the pathogenesis of early-stage colon adenocarcinoma which may make a contribution for developing new diagnostic and therapeutic strategies for early-Stage colon adnoccarinoma. Expand
Surgical management for non-functional pancreatic neuroendocrine neoplasms with synchronous liver metastasis: A consensus from the Chinese Study Group for Neuroendocrine Tumors (CSNET).
TLDR
Based on updated literature review, the treatment strategy determinants for p-NEN with LM are discussed and insufficient evidence exists to guide the surgical treatment of G3 p-NET with LM. Expand
Concurrent chemoradiotherapy with or without adjuvant chemotherapy in intermediate and locoregionally advanced nasopharyngeal carcinoma
TLDR
No evidence was found of an additional value of AC in CCRT treatment in disease control and clinical outcomes in patients with locally advanced NPC in endemic regions, and AC should not be routinely used for treatment, although clinical trials may be justified. Expand
Increased mortality for colorectal cancer patients with preexisting diabetes mellitus: an updated meta-analysis
TLDR
It is indicated that preexisting diabetes mellitus in CRC patients is severely associated with the worse overall survival but not with cancer-specific survival. Expand
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