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Electroacupuncture: mechanisms and clinical application

• George A. Ulett, Songping Han, Ji-sheng Han
• Biological Psychiatry
• 1998

Acupuncture is an ancient Chinese method to treat diseases and relieve pain. We have conducted a series of studies to examine the mechanisms of this ancient method for pain relief. This article… (More)

Accelerated release and production of orphanin FQ in brain of chronic morphine tolerant rats

• Li Yuan, Zhou Han, J. K. Chang, Ji-sheng Han
• Brain Research
• 1999

Orphanin FQ has been shown to possess anti-opioid activity at supraspinal level. Our previous work revealed that chronic morphine tolerance could be reversed by intracerebroventricular (i.c.v.)… (More)

Increase of success rate for women undergoing embryo transfer by transcutaneous electrical acupoint stimulation: a prospective randomized placebo-controlled study.

• Rong Zhang, Xiao-Jun Feng, +4 authors Ji-sheng Han
• Fertility and sterility
• 2011

OBJECTIVE To evaluate the effect of transcutaneous electrical acupoint stimulation (TEAS) on pregnancy rates (PR) in women undergoing ET. DESIGN Prospective, randomized, single-blinded… (More)

Analgesia induced by electroacupuncture of different frequencies is mediated by different types of opioid receptors: another cross-tolerance study

• Xiao-Hong Chen, Ji-sheng Han
• Behavioural Brain Research
• 1992

The cross-tolerance technique was used to analyze the receptor mechanisms of analgesia induced by electroacupuncture (EA) of 2 Hz, 100 Hz, or 2-15 Hz. (1) Rats were given EA stimulation of 2 Hz, 100… (More)

Physiology of Acupuncture: Review of Thirty Years of Research

• Ji-sheng Han
• 1997

Acupuncture and electroacupuncture effects are mediated through a variety of neural and neurochemical mechanisms. Research done in the early 1970s first elucidated the mechanisms for the effect of… (More)

Is cholecystokinin octapeptide (CCK-8) a candidate for endogenous antiopioid substrates?

• Ji-sheng Han, Xuan-Zhou Ding, Shao-Guan Fan
• Neuropeptides
• 1985

Cholecystokinin octapeptide (CCK-8), given intracerebroventricularly (icv) or intrathecally (ith) at the dose range of 0.25-4.0 ng, dose-dependently antagonised the effect of morphine analgesia and… (More)

Cholecystokinin-octapeptide antagonizes morphine analgesia in periaqueductal gray of the rat

• Yan Li, Ji-sheng Han
• Brain Research
• 1989

The analgesic effect of systemic morphine (5 mg/kg, s.c.) was dose-dependently antagonized by CCK-8 administered to the periaqueductal gray (PAG) of the rat. This effect could be reversed by… (More)

Suppression of morphine withdrawal by electroacupuncture in rats: dynorphin and κ-opioid receptor implicated

• Liu-Zhen Wu, Cai-lian Cui, Jin-Bin Tian, Dong Ji, Ji-sheng Han
• Brain Research
• 1999

Our previous work has demonstrated that 100-Hz electroacupuncture (EA) or 100-Hz transcutaneous electrical nerve stimulation (TENS) was very effective in ameliorating the morphine withdrawal syndrome… (More)

Endomorphin and μ-opioid receptors in mouse brain mediate the analgesic effect induced by 2 Hz but not 100 Hz electroacupuncture stimulation

• Chunyue Huang, Yun Wang, J. K. Chang, Ji-sheng Han
• Neuroscience Letters
• 2000

This work was designed to examine whether brain endomorphins (EM1 and EM2), the endogenous mu-opioid ligands, are involved in electroacupuncture (EA)-induced analgesia in the mice. C57BL/6J mice were… (More)

Functional studies using antibodies against orphanin FQ/nociceptin

• Jin-hua Tian, Ji-sheng Han
• Peptides
• 2000

Orphanin FQ/nociceptin (OFQ) is a recently discovered endogenous ligand for the novel opioid receptor-like receptor (ORL-1). There are numerous reports in the literature demonstrating paradoxical… (More)

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