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Urinary nerve-growth-factor (NGF) level reflected the severity of urgency in patients with lower urinary tract symptoms (LUTS) and pain in patients with Bladder pain syndrome/interstitial cystitis (BPS/IC). The aim of this study was to investigate the levels of biomarkers, nerve growth factor (NGF), and prostaglandin E2 (PGE2) among disease groups sharing(More)
We thank Agilli et al. [1] for their discussion of the restricted exclusion criteria in our study and possible effects of systemic conditions, including neuropsychiatric diseases and diabetes, on urinary nerve growth factor (NGF) [2]. NGF messenger RNA (mRNA) expression and protein production was described in various cells, including smooth muscle cells,(More)
1. Agilli M, Aydin FN, Kurt YG, Cayci T (2014) Urinary nerve growth factor correlates with the severity of urgency and pain: methodological evaluation. Int Urogynecol J. doi:10.1007/s00192-014-2532-5 2. Kim SW, Im YJ, Choi HC, Kang HJ, Kim JY, Kim JH (2014) Urinary nerve growth factor correlates with the severity of urgency and pain. Int Urogynecol J(More)
AIMS To evaluate the correlation between symptom severity of bladder pain syndrome/interstitial cystitis (BPS/IC) and autonomic nervous system activity, we examined autonomic responses during bladder hydrodistention. METHODS Medical records were collected from a prospective database for patients who underwent bladder hydrodistention with a fixed protocol(More)
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