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[24] R. Shadmehr and F. A. Mussa-Ivaldi, " Adaptive representation of dynamics during learning of a motor task, " The nervous system appears to minimize a weighted sum of kinematic error, force, and change in force when adapting to viscous environments during reaching and stepping. presented at Adv. [26] J. L. Emken and D. J. Reinkensmeyer, " Robot-enhanced(More)
Kainic acid (KA) induced oxidative stress is associated with hippocampal cell death. Recent studies suggest that curcumin, a potent antioxidant, may provide protection for KA-induced oxidative stress. We investigated the effects of curcumin treatment on hippocampal reactive astrocytes in mice with KA-induced seizures. Eighteen hours after curcumin(More)
We present a new algorithm that enables a convex shaped robot to explore an unknown planar workspace, i.e., an unknown configuration space diffeomorphic to SE(2). This new algorithm is based on a new roadmap called the convex hierarchical generalized Voronoi graph (convex-HGVG), which is the central contribution of this paper. Since this roadmap is defined(More)
—Sensor-based planning for rod-shaped robots is necessary for the realistic deployment of noncircularly symmetric robots into unknown environments. Whereas circularly symmetric robots have two-dimensional Euclidean configuration spaces, planar rod robots posses three degrees-of-freedom, two for position and one for orientation, and hence have a(More)
We present a new roadmap for a rod-shaped robot operating in a three-dimensional workspace, whose configuration space is diffeo-morphic to R 3 × S 2. This roadmap is called the rod hierarchical generalized Voronoi graph (rod-HGVG) and can be used to find a path between any two points in an unknown configuration space using only the sensor data. More(More)
Kainic acid (KA)-induced seizure induces the hippocampal cell death. There are reports that AMP-activated protein kinase (AMPK), which is an important regulator of energy homeostasis of cells, has been proposed as apoptotic molecule. In this study, we investigated the altered expression of AMPK cascade in the hippocampus of mice during KA-induced(More)