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In situ Detection of a Single Bacterium in Complex Environment by Hyperspectral CARS Imaging
Detection of bacteria is essential for clinical diagnosis of infectious disease and food safety purposes. However, it is still a challenging task to rapidly detect bacteria, especially in theirExpand
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Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D2O Metabolic Incorporation in a Single Bacterium
Abstract Rapid antimicrobial susceptibility testing (AST) is urgently needed for treating infections with appropriate antibiotics and slowing down the emergence of antibiotic‐resistant bacteria.Expand
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Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography.
TLDR
We develop a urethral device with cylindrical illumination for whole-prostate imaging, and its performance as a function of angular light coupling is evaluated with a prostatic phantom. Expand
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Label-free quantitation of glycated hemoglobin in single red blood cells by transient absorption microscopy and phasor analysis
Transient absorption microscopy could detect HbA1c, which is a stable biomarker for diabetes, at single–red blood cell level. As a stable and accurate biomarker, glycated hemoglobin (HbA1c) isExpand
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Transient absorption microscopy: Technological innovations and applications in materials science and life science.
Transient absorption (TA) spectroscopy has been extensively used in the study of excited state dynamics of various materials and molecules. The transition from TA spectroscopy to TA microscopy, whichExpand
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Multiplex Stimulated Raman Scattering Imaging Cytometry Reveals Lipid-Rich Protrusions in Cancer Cells under Stress Condition
Summary In situ measurement of cellular metabolites is still a challenge in biology. Conventional methods, such as mass spectrometry or fluorescence microscopy, would either destroy the sample orExpand
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Photo‐Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA
Abstract Confronted with the rapid evolution and dissemination of antibiotic resistance, there is an urgent need to develop alternative treatment strategies for drug‐resistant pathogens. Here, anExpand
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A Thermodynamic Interpretation of the Stimulated Raman Spectroscopic Signature of an Action Potential in a Single Neuron
It has previously been suggested that the plasma membrane condenses and melts reversibly during an action potential in a neuron, analogous to an acoustic wave travelling in the compressive membraneExpand
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Functionalized NIR-II Semiconducting Polymer Nanoparticles for Single-cell to Whole-Organ Imaging of PSMA-Positive Prostate Cancer.
Development of molecular probes holds great promise for early diagnosis of aggressive prostate cancer. Here, 2-[3-(1,3-dicarboxypropyl) ureido] pentanedioic acid (DUPA)-conjugated ligand andExpand
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Dual-wavelength photo-killing of methicillin-resistant Staphylococcus aureus.
With the effectiveness of antimicrobials declining as antimicrobial resistance continues to threaten public health, we must look to alternative strategies for the treatment of infections. In thisExpand
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