Ji-Hoon Kang

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Recently, it was reported that in a 4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model, neuronal cell death is associated with the cdk5-mediated hyperphosphorylation of myocyte enhancer factor 2 (MEF2), a transcription factor that is critically required for neuronal survival. In the present study, we investigated the possible involvement of cdk5-mediated(More)
Because of frequent involvement of the cerebellum and brainstem, ocular motor abnormalities are key features of spinocerebellar ataxias and may aid in differential diagnosis. Our objective for this study was to distinguish the subtypes by ophthalmologic features after head-shaking and positional maneuvers, which are not yet recognized as differential(More)
Intracerebral hemorrhage (ICH) has been described only sporadically for patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). However, cerebral microbleeds (CMBs) were found in 31% to 69% of the patients with CADASIL, and this predicted an increased risk of ICH. In this study, the authors found(More)
XML is now a standard markup language for web information. Many application areas are producing XML documents on the web. This situation urges digital library systems to deal with not only typical text documents but also XML documents. XML documents are semi-structured. Some queries based on the structures are useful and necessary.MPEG-7 is a metadata(More)
We designed and implemented a digital library system that supports content-based retrieval of multimedia objects based on MPEG-7 and XQuery. MPEG-7, a metadata standard for multimedia objects, can describe various features such as color histograms of images and content descriptors. As such, a multimedia digital library system built with MPEG-7 metadata can(More)
BACKGROUND AND PURPOSE Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited microangiopathy caused by mutations in the Notch3 gene. Although previous studies have shown an association between lacunar infarction and cognitive impairment, the relationship between MRI parameters and cognition(More)